CAS 69712-56-7

Cefotetan

Description:

Cefotetan is a broad-spectrum cephalosporin antibiotic, classified under the second generation of cephalosporins. It is primarily used to treat a variety of bacterial infections, particularly those caused by Gram-negative bacteria. Cefotetan exhibits a beta-lactam structure, which is essential for its antibacterial activity, as it interferes with bacterial cell wall synthesis. This compound is effective against a range of pathogens, including Escherichia coli and Klebsiella pneumoniae. Cefotetan is typically administered via intravenous or intramuscular routes, and it is known for its relatively low toxicity profile. One of its notable characteristics is its ability to inhibit certain beta-lactamases, enzymes that can confer resistance to other antibiotics. Additionally, cefotetan has a side chain that provides stability against some beta-lactamase enzymes, enhancing its efficacy. Common side effects may include gastrointestinal disturbances and allergic reactions, similar to other beta-lactam antibiotics. Overall, cefotetan is a valuable option in the treatment of infections, particularly in surgical prophylaxis and in cases where resistance to other antibiotics is a concern.

Formula: C₁₇H₁₇N₇O₈S₄

InChI: InChI=1/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/b12-6-/t13?,15-,17+/m1/s1

InChI key: InChIKey=SRZNHPXWXCNNDU-RHBCBLIFSA-N

SMILES: N(C(=O)C1SC(=C(C(N)=O)C(O)=O)S1)[C@@]2(OC)[C@@]3(N(C2=O)C(C(O)=O)=C(CSC=4N(C)N=NN4)CS3)[H]

Synonyms:

• (6R,7S)-7-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7S)-7-[[4-(1-Amino-3-hydroxy-1,3-dioxopropan-2-ylidene)1,3-dithietane-2-carbonyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7S)-7-[[[4-(2-Amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (7S)-7-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7-(methyloxy)-3-{[(1-methyl-1H-tetrazol-5-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (7S)-7-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 1,3-Dithietane, 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid deriv.
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R,7S)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, [6R-(6α,7α)]-
• 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (7S)-
• Apacef
• [6R-(6α,7α)-7-[[[4-(2-Amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Cefotetan
• Cefotetansodiumsalt
• Cepan Darvilen
• y-2-oxoethylidene)-1,3-dithietan-2-yl)carbonyl)amino)-7-methoxy-3-(((1-methyl
• CEFOTETAN DISODIUM SALT
• Ceftenon
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, disodium salt, [6R-(6alpha,7alpha)]-
• CEFOTETAN SODIUM
• (6r-(6-alpha,7-alpha))--1h-tetrazol-5-yl)thio)methyl)-8-oxo
• disodium (7r)-7-[[4-(carbamoyl-carboxylato-methylidene)-1,3-dithietane-2-carbonyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Apatef
• CefotetanDisodiumC17H15N7Na2O8S4
• [6R-(6ALPHA,7ALPHA)]-7-[[[4-(2-AMINO-1-CARBOXY-2-OXOETHYLIDENE)-1,3-DITHIETAN-2-YL]CARBONYL]AMINO]-7-METHOXY-3-[[(1-METHYL-1H-TETRAZOL-5-YL)THIO]METHYL]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, disodium salt, (6R,7S)-
• 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-(((4-(2-amino-1-carbox

Cefotetan

CAS: 69712-56-7

Antibiotics nesoi

Formula: C₁₇H₁₇N₇O₈S₄

Color and Shape: Powder

Molecular weight: 575.62

Ref: 45-1097975

(6R,7S)-7-[[[4-(2-Amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS: 69712-56-7

Formula: C₁₇H₁₇N₇O₈S₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 575.6190

Ref: IN-DA0068RA

Cefotetan

CAS: 69712-56-7

Cefotetan

Color and Shape: White-Pale Yellow Powder

Molecular weight: 575.62g/mol

Ref: 54-BIC0104

Cefotetan

CAS: 69712-56-7

Cefotetan

Purity: ≥95%

Molecular weight: 575.62g/mol

Ref: 54-BUP10538

Cefotetan

CAS: 69712-56-7

Formula: C₁₇H₁₇N₇O₈S₄

Purity: 96.0 - 102.0 %

Color and Shape: White to pale yellow crystalline powder

Molecular weight: 575.60

Ref: 7W-GA2551

Cefotetan

CAS: 69712-56-7

Cefotetan, a cephamycin antibiotic, fights various bacteria by disrupting cell wall synthesis.

Formula: C₁₇H₁₇N₇O₈S₄

Purity: 95.72% - 99.38%

Color and Shape: Solid

Molecular weight: 575.62

Ref: TM-T7043

Cefotetan

CAS: 69712-56-7

Formula: C₁₇H₁₇N₇O₈S₄

Molecular weight: 575.62

Ref: 4Z-C-243001

Cefotetan

Controlled Product

CAS: 69712-56-7

Stability Hygroscopic
Applications An antibiotic related to Cephalosporin, used in the treatment of bacterial infections.
References Ahmed, A., et al.: Vet. Microbiol., 136, 397 (2009), Kim, M., et al.: J. Bacteriol. Virol., 39, 29 (2009), Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010),

Formula: C₁₇H₁₇N₇O₈S₄

Color and Shape: White To Light Yellow

Molecular weight: 575.62

Ref: TR-C242970

Cefotetan

CAS: 69712-56-7

Inhibitor of cell wall synthesis; cephalosporin class

Formula: C₁₇H₁₇N₇O₈S₄

Purity: Min. 96 Area-%

Color and Shape: Powder

Molecular weight: 575.62 g/mol

Ref: 3D-FA19861

Cefotetan

CAS: 69712-56-7

Formula: C₁₇H₁₇N₇O₈S₄

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 575.60

Ref: 3B-C2936

Cefotetan-13C3

Controlled Product

CAS: 69712-56-7

Formula: C₃C₁₄H₁₇N₇O₈S₄

Color and Shape: Neat

Molecular weight: 578.597

Ref: TR-C242972