CAS 697287-17-5

(3R,4R,5R,6R)-6-[2-[2-(2-chloro-6-fluoro-anilino)-5-methyl-phenyl]acetyl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid

Description:

The chemical substance with the name "(3R,4R,5R,6R)-6-[2-[2-(2-chloro-6-fluoro-anilino)-5-methyl-phenyl]acetyl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid" and CAS number "697287-17-5" is a complex organic compound characterized by its tetrahydropyran structure, which features multiple hydroxyl groups contributing to its hydrophilicity. The presence of a carboxylic acid group enhances its acidity and potential for forming salts. The compound also contains a chloro-fluoro-substituted aniline moiety, which may influence its biological activity and interactions. The stereochemistry indicated by the (3R,4R,5R,6R) configuration suggests specific spatial arrangements that can affect the compound's reactivity and binding properties in biological systems. This compound may exhibit pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. Its complex structure and functional groups suggest potential interactions with various biological targets, warranting further investigation into its efficacy and safety profiles.

Formula: C₂₁H₂₁ClFNO₈

InChI: InChI=1/C21H21ClFNO8/c1-9-5-6-13(24-15-11(22)3-2-4-12(15)23)10(7-9)8-14(25)31-21-18(28)16(26)17(27)19(32-21)20(29)30/h2-7,16-19,21,24,26-28H,8H2,1H3,(H,29,30)/t16-,17-,18-,19?,21+/m1/s1

Lumiracoxib-acyl-β-D-glucuronide

CAS: 697287-17-5

Lumiracoxib-acyl-β-D-glucuronide

Purity: >93.8%

Molecular weight: 469.84g/mol

Ref: 54-BICL4126

Lumiracoxib acyl-b-D-glucuronide

CAS: 697287-17-5

Ref: 7W-GC0838

Lumiracoxib acyl-β-D-glucuronide

Controlled Product

CAS: 697287-17-5

Lumiracoxib acyl-b-D-glucuronide is a synthetic compound that is a derivative of the nonsteroidal anti-inflammatory drug lumiracoxib. It has been shown to be effective as an inhibitor of inflammation and pain in animal models, with no significant toxic effects on the liver or kidney. Lumiracoxib acyl-b-D-glucuronide is a white powder that can be synthesized by glycosylation and modification of lumiracoxib. This compound is soluble in water and ethanol, but insoluble in ether.

Formula: C₂₁H₂₁ClFNO₈

Purity: Min. 95%

Color and Shape: White To Yellow Solid

Molecular weight: 469.84 g/mol

Ref: 3D-ML10284

Lumiracoxib Acyl-β-D-glucuronide

Controlled Product

CAS: 697287-17-5

Stability Moisture Sensitive, Temperature Sensitive
Applications A metabolite of Lumiracoxib.
References Fu, J., et al.: J. Biol. Chem., 265, 16737 (1990), Goldstein, J., et al.: Am. J. Gastroenterol., 96, 1019 (2001), Flower, R., et al.: Nat. Rev. Drug Discov., 2, 179 (2003), Grillo, M., et al.: Drug Metab. Dispos., 31, 1327 (2003),

Formula: C₂₁H₂₁ClFNO₈

Color and Shape: Neat

Molecular weight: 469.84

Ref: TR-L474710