CAS 6973-09-7

5-Amino-2-methylbenzenesulfonamide

Description:

5-Amino-2-methylbenzenesulfonamide, also known as sulfamethoxazole, is an organic compound characterized by its sulfonamide functional group, which is a key feature of many antibacterial agents. This compound has a molecular structure that includes an amino group and a methyl group attached to a benzene ring, along with a sulfonamide moiety. It is typically a white to off-white crystalline solid that is soluble in water and exhibits moderate stability under standard conditions. The presence of the amino group contributes to its basicity, while the sulfonamide group is responsible for its antibacterial properties, as it inhibits bacterial growth by interfering with folic acid synthesis. 5-Amino-2-methylbenzenesulfonamide is commonly used in the pharmaceutical industry, particularly in the formulation of antibiotics, and is known for its effectiveness against a range of bacterial infections. Its safety profile and pharmacokinetics are well-studied, making it a significant compound in medicinal chemistry.

Formula: C₇H₁₀N₂O₂S

InChI: InChI=1S/C7H10N2O2S/c1-5-2-3-6(8)4-7(5)12(9,10)11/h2-4H,8H2,1H3,(H2,9,10,11)

InChI key: InChIKey=KTPBKMYOIFHJMI-UHFFFAOYSA-N

SMILES: S(N)(=O)(=O)C1=C(C)C=CC(N)=C1

Synonyms:

• 2-Methyl-5-Aminobenzene Sulfonamide
• 2-Methyl-5-amino-benzenesulfonamide
• 3-Amino-6-Methyl Benzene Sulphonamide
• 3-Amino-6-methylbenzene sulfonamide
• 3-Amino-6-methylbenzenesulfonamide
• 3-Aminosulfonyl-4-methylaniline
• Benzenesulfonamide, 5-amino-2-methyl-
• NSC 36969
• 5-Amino-2-methylbenzenesulfonamide

5-Amino-2-methylbenzenesulfonamide

CAS: 6973-09-7

Formula: C₇H₁₀N₂O₂S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 186.23

Ref: 3B-A2552

5-Amino-2-methylbenzenesulfonamide, 96%

CAS: 6973-09-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₁₀N₂O₂S

Purity: 96%

Color and Shape: Powder, Pale cream

Molecular weight: 186.23

Ref: 02-H34056

3-Amino-6-methylbenzenesulfonamide

CAS: 6973-09-7

Formula: C₇H₁₀N₂O₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 186.2315

Ref: IN-DA0033LB

Pazopanib Impurity 16

CAS: 6973-09-7

Formula: C₇H₁₀N₂O₂S

Color and Shape: Yellow Solid

Molecular weight: 186.23

Ref: 4Z-P-129023

5-Amino-2-Methylbenzenesulfonamide

CAS: 6973-09-7

5-Amino-2-Methylbenzenesulfonamide

Purity: 98%

Molecular weight: 186.23g/mol

Ref: 54-OR1011805

5-Amino-2-methyl-benzenesulfonamide

Controlled Product

CAS: 6973-09-7

Applications 5-amino-2-methyl-benzenesulfonamide (cas# 6973-09-7) is a useful research chemical.

Formula: C₇H₁₀N₂O₂S

Color and Shape: Neat

Molecular weight: 186.23

Ref: TR-A614668

5-Amino-2-methylbenzenesulfonamide

CAS: 6973-09-7

Formula: C₇H₁₀N₂O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 186.23

Ref: 10-F078148

5-Amino-2-methylbenzenesulfonamide

Controlled Product

CAS: 6973-09-7

Stability Hygroscopic
Applications 5-Amino-2-methylbenzenesulfonamide is an intermediate for the synthesis of Pazopanib (P210925), an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
References Harris, P.A., et al.: J. Med. Chem., 51, 4632 (2008); Petrow, V., et al.: J. Pharmacy. Pharmacol., 12, 705 (1960);

Formula: C₇H₁₀N₂O₂S

Color and Shape: Neat

Molecular weight: 186.23

Ref: TR-A612030

Pazopanib Impurity 14

CAS: 6973-09-7

Formula: C₇H₁₀N₂O₂S

Molecular weight: 186.23

Ref: ST-EA-CP-P58015