CAS 69739-34-0

(1,1-Dimethylethyl)dimethylsilyl 1,1,1-trifluoromethanesulfonate

Description:

(1,1-Dimethylethyl)dimethylsilyl 1,1,1-trifluoromethanesulfonate, with CAS number 69739-34-0, is a chemical compound characterized by its unique structure that includes a silyl group and a trifluoromethanesulfonate moiety. This compound typically appears as a colorless to pale yellow liquid and is known for its reactivity, particularly in nucleophilic substitution reactions. The presence of the trifluoromethanesulfonate group imparts strong electrophilic properties, making it a useful reagent in organic synthesis, especially for the introduction of silyl groups into various substrates. Its dimethylsilyl component enhances its stability and solubility in organic solvents. Additionally, the compound is sensitive to moisture and should be handled under anhydrous conditions to prevent hydrolysis. Safety precautions are essential when working with this substance, as it may pose health hazards if inhaled or in contact with skin. Overall, (1,1-Dimethylethyl)dimethylsilyl 1,1,1-trifluoromethanesulfonate is a valuable tool in synthetic organic chemistry, particularly in the field of silylation reactions.

Formula: C₇H₁₅F₃O₃SSi

InChI: InChI=1S/C7H15F3O3SSi/c1-6(2,3)15(4,5)13-14(11,12)7(8,9)10/h1-5H3

InChI key: InChIKey=WLLIXJBWWFGEHT-UHFFFAOYSA-N

SMILES: S(O[Si](C(C)(C)C)(C)C)(C(F)(F)F)(=O)=O

Synonyms:

• (1,1-Dimethylethyl)dimethylsilyl 1,1,1-trifluoromethanesulfonate
• (1,1-Dimethylethyl)dimethylsilyl trifluoromethanesulfonate
• (tert-Butyl-dimethylsilyl) trifluoromethanesulfonate
• 2-(Chloromethyl)-1,3-Difluorobenzene
• Dimethyl(2-methyl-2-propanyl)silyl trifluoromethanesulfonate
• Methanesulfonic acid, 1,1,1-trifluoro-, (1,1-dimethylethyl)dimethylsilyl ester
• Methanesulfonic acid, trifluoro-, (1,1-dimethylethyl)dimethylsilyl ester
• Tert-Butyl Dimethylsilyl trifluoromethane sulphonate
• Tert-Butyl(Methoxy)Diphenylsilane
• Trifluoromethanesulfonic Acid Tert-Butyldimethylsilyl Ester
• Trifluoromethanesulfonic acid (1,1-dimethylethyl)dimethylsilyl ester
• tert-Butyldimethylsilyl triflate
• tert-Butyldimethylsilyl trifluoromethanesulfonate

tert-Butyldimethylsilyl Trifluoromethanesulfonate

CAS: 69739-34-0

Formula: C₇H₁₅F₃O₃SSi

Purity: >98.0%(T)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 264.33

Ref: 3B-T1525

tert-Butyldimethylsilyl trifluoromethanesulfonate, 98%

CAS: 69739-34-0

tert-Butyldimethylsilyl trifluoromethanesulfonate is involved in the introduction of a bulky tert-butyl dimethylsilyl group onto a cis-bis(alkenyl)oxirane used in Cope rearrangement. It is associated with a thiolane and promotes the chalcogenide-Morita-Baylis-Hillman reaction. Further, it is used as

Formula: C₇H₁₅F₃O₃SSi

Purity: 98%

Color and Shape: Clear colorless to yellow, Liquid

Molecular weight: 264.33

Ref: 02-A12174

t-Butyldimethylsilyl trifluoromethanesulfonate, 98%

CAS: 69739-34-0

t-Butyldimethylsilyl trifluoromethanesulfonate, 98%

Formula: (C₄H₉)(CH₃)₂Si(SO₃CF₃)

Purity: 98%

Color and Shape: clear liq.

Molecular weight: 264.34

Ref: 08-14-1800

tert-Butyldimethylsilyl trifluoromethanesulfonate

CAS: 69739-34-0

Formula: C₇H₁₅F₃O₃SSi

Purity: 95%

Color and Shape: Liquid

Molecular weight: 264.3379

Ref: IN-DA0035QY

tert-Butyldimethylsilyl trifluoromethanesulfonate

CAS: 69739-34-0

Formula: C₇H₁₅F₃O₃SSi

Purity: ≥ 99.0%

Color and Shape: Colourless to light-yellow liquid

Molecular weight: 264.34

Ref: 7W-GK6494

tert-Butyldimethylsilyl trifluoromethanesulphonate

CAS: 69739-34-0

tert-Butyldimethylsilyl trifluoromethanesulphonate

Formula: C₇H₁₅F₃O₃SSi

Purity: 95%

Color and Shape: clear. almost colourless liquid

Molecular weight: 264.3379g/mol

Ref: 54-PC1605

tert-Butyldimethylsilyl trifluoromethanesulphonate

CAS: 69739-34-0

S03375 - tert-Butyldimethylsilyl trifluoromethanesulphonate

Formula: C₇H₁₅F₃O₃SSi

Purity: 98%

Color and Shape: Liquid

Molecular weight: 264.33

Ref: 10-S03375

tert-Butyldimethylsilyl trifluoromethanesulfonate

CAS: 69739-34-0

tert-Butyldimethylsilyl trifluoromethanesulfonate is a nucleophilic reagent that forms an addition product with metal carbonyls. It can be used for the synthesis of indacaterol maleate, which is a phosphite prodrug for the treatment of asthma and chronic obstructive pulmonary disease. Tert-butyldimethylsilyl trifluoromethanesulfonate has been shown to catalyze asymmetric hydrogenation reactions in the presence of ammonia as a chiral auxiliary. This reagent has also been shown to inhibit the growth of bacteria and fungi through its ability to inhibit protein synthesis.

Formula: C₇H₁₅F₃O₃SSi

Color and Shape: Colorless Clear Liquid

Molecular weight: 264.34 g/mol

Ref: 3D-FB53762

t-BUTYLDIMETHYLSILYLTRIFLUOROMETHANESULFONATE

CAS: 69739-34-0

Trialkylsilyl Blocking Agent
Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.
tert-Butyldimethylsilyltrifluoromethanesulfonate; TBS-OTf; t-Butyldimethylsilyltriflate
More reactive than SIB1935.0Converts acetates to TBS ethersUsed for the protection of alcohols, amines, thiols, lactams, and carboxylic acidsClean NMR characteristics of protecting groupFacile removal with flouride ion sourcesSummary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure

Formula: C₇H₁₅F₃O₃SSi

Color and Shape: Straw Liquid

Molecular weight: 264.33

Ref: 3H-SIB1967.0

tert-Butyldimethylsilyl Trifluoromethanesulfonate

Controlled Product

CAS: 69739-34-0

Stability Moisture Sensitive
Applications Tert-Butyldimethylsilyl Trifluoromethanesulfonate is a highly reactive silylating agent and lewis acid capable of converting primary, secondary and tertiary alcohols to their respectctive TBDMS. Tert-Butyldimethylsilyl Trifluoromethanesulfonate is also used to covert ketones and lactones into their enol silyl ethers.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hua, D.H. et al.: e-ROS Encyc. Reag. Org. Synth., No pp. given (2001); Suzuki, T. et al.: Synthesis, 4, 555 (2001);

Formula: C₇H₁₅F₃O₃SSi

Color and Shape: Neat

Molecular weight: 264.34

Ref: TR-B691775

tert-Butyldimethylsilyl trifluoromethanesulphonate

CAS: 69739-34-0

Formula: C₇H₁₅F₃SSiO₃

Purity: 98%

Color and Shape: Liquid, Clear

Molecular weight: 264.33

Ref: 10-S25396

tert-Butyldimethylsilyl Trifluoromethanesulfonate (TBDMS triflate) extrapure, 98%

CAS: 69739-34-0

Formula: C₇H₁₅O₃SSiF₃

Purity: min. 98%

Color and Shape: Clear, Colourless,fuming, Liquid

Molecular weight: 264.34

Ref: SR-52573

tert-Butyldimethylsilyl trifluoromethanesulphonate

CAS: 69739-34-0

Purity: 95%

Molecular weight: 264.046

Ref: 10-F570009