CAS 69759-61-1

2,7-Dichloro-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol

Description:

2,7-Dichloro-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol is a chemical compound characterized by its complex structure, which includes a fluorene backbone substituted with chlorine and a dibutylamino group. This compound typically exhibits properties associated with both organic amines and chlorinated aromatic compounds. It is likely to be a solid at room temperature, with potential applications in organic synthesis or as a pharmaceutical intermediate due to its unique functional groups. The presence of the hydroxymethyl group suggests it may participate in hydrogen bonding, influencing its solubility and reactivity. Additionally, the chlorinated sites may impart specific electronic properties, making it useful in various chemical reactions. Safety data should be consulted, as chlorinated compounds can pose environmental and health risks. Overall, this compound's characteristics make it a subject of interest in both academic research and industrial applications, particularly in the fields of medicinal chemistry and materials science.

Formula: C₂₃H₂₉Cl₂NO

InChI: InChI=1S/C23H29Cl2NO/c1-3-5-9-26(10-6-4-2)15-22(27)21-14-19(25)13-17-11-16-12-18(24)7-8-20(16)23(17)21/h7-8,12-14,22,27H,3-6,9-11,15H2,1-2H3

InChI key: InChIKey=DALUOHFKVYCDCW-UHFFFAOYSA-N

SMILES: C(CN(CCCC)CCCC)(O)C1=C2C=3C(CC2=CC(Cl)=C1)=CC(Cl)=CC3

Synonyms:

• 2,7-Dichloro-α-(Dibutylamino)methyl-9H-Fluorene-4-Methanol
• 2-(Dibutylamino)-1-(2,7-dichloro-9H-fluoren-4-yl)ethanol
• 9H-Fluorene-4-methanol, 2,7-dichloro-α-[(dibutylamino)methyl]-

2,7-Dichloro-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol

CAS: 69759-61-1

Formula: C₂₃H₂₉Cl₂NO

Purity: 97%

Color and Shape: Solid

Molecular weight: 406.3885

Ref: IN-DA005I0W

2,7-Dichloro-α-[(Dibutylamino)Methyl]-9H-Fluorene-4-Methanol

CAS: 69759-61-1

2,7-Dichloro-α-[(Dibutylamino)Methyl]-9H-Fluorene-4-Methanol

Purity: 98%

Molecular weight: 406.39g/mol

Ref: 54-OR1010201

2-(Dibutylamino)-1-(2,7-dichloro-9H-fluoren-4-yl)ethanol

CAS: 69759-61-1

Formula: C₂₃H₂₉Cl₂NO

Molecular weight: 406.40

Ref: 4Z-L-298

2-(Dibutylamino)-1-(2,7-dichloro-9H-fluoren-4-yl)ethanol

CAS: 69759-61-1

Applications 2-(Dibutylamino)-1-(2,7-dichloror-9H-fluoren-4-yl)ethanol is an impurity formed during the synthesis of Lumefantrine (L474000), a fluorene (F462000) derivative belonging to the aryl amino alcohol class of anti-malarial drugs.
References Verbeken, M., et al.: Malaria. J., 10, 51 (2011); Kim, K.H., et al.: J. Med. Chem., 22, 366 (1979);

Formula: C₂₃H₂₉Cl₂NO

Color and Shape: Neat

Molecular weight: 406.39

Ref: TR-D426750