CAS 697761-98-1
:Elvitegravir
Description:
Elvitegravir is an antiretroviral medication primarily used in the treatment of HIV infection. It belongs to the class of drugs known as integrase strand transfer inhibitors (INSTIs), which work by blocking the integrase enzyme, thereby preventing the integration of viral DNA into the host cell's genome. Elvitegravir is typically administered in combination with other antiretroviral agents to enhance its efficacy and reduce the potential for resistance. The substance is characterized by its molecular formula, which reflects its complex structure, and it exhibits a moderate solubility in water, making it suitable for oral administration. Elvitegravir is often formulated as part of fixed-dose combinations, which simplifies treatment regimens for patients. Its pharmacokinetics are influenced by food intake, with enhanced absorption when taken with meals. Common side effects may include gastrointestinal disturbances, fatigue, and potential impacts on renal function, necessitating monitoring during treatment. Overall, Elvitegravir represents a significant advancement in HIV therapy, contributing to improved patient outcomes.
Formula:C23H23ClFNO5
InChI:InChI=1S/C23H23ClFNO5/c1-12(2)19(11-27)26-10-16(23(29)30)22(28)15-8-14(20(31-3)9-18(15)26)7-13-5-4-6-17(24)21(13)25/h4-6,8-10,12,19,27H,7,11H2,1-3H3,(H,29,30)/t19-/m1/s1
InChI key:InChIKey=JUZYLCPPVHEVSV-LJQANCHMSA-N
SMILES:[C@H](C(C)C)(CO)N1C=2C(=CC(CC3=C(F)C(Cl)=CC=C3)=C(OC)C2)C(=O)C(C(O)=O)=C1
Synonyms:- (S)-6-(3-Chloro-2-fluorobenzyl)-1-(1-hydroxy-3-methylbutan-2-yl)-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
- 1,4-Dihydro-6-(3-chloro-2-fluorobenzyl)-7-methoxy-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-4-oxo-3-quinolinecarboxylic acid
- 3-Quinolinecarboxylic acid, 6-[(3-chloro-2-fluorophenyl)methyl]-1,4-dihydro-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-
- 6-(3-Chloro-2-Fluorobenzyl)-1-[1-(Hydroxymethyl)-2-Methylpropyl]-7-Methoxy-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
- 6-(3-Chloro-2-fluorobenzyl)-1-[(S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
- 6-(3-Chloro-2-fluorobenzyl)-1-[1(S)-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
- 6-[(3-Chloro-2-fluorophenyl)methyl]-1,4-dihydro-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-3-quinolinecarboxylic acid
- Gs-9137
- Jtk-303
- Vitekta
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Found 12 products.
Elvitegravir-d8
CAS:Formula:C23H15D8ClFNO5Color and Shape:White To Off-White SolidMolecular weight:455.94Elvitegravir
CAS:Formula:C23H23ClFNO5Purity:>95.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:447.89Elvitegravir
CAS:Formula:C23H23ClFNO5Purity:≥ 98.0%Color and Shape:White to off-white powder or solidMolecular weight:447.88Elvitegravir
CAS:<p>Elvitegravir (JTK-303) is an HIV integrase inhibitor and CYP2C9 inducer.</p>Formula:C23H23ClFNO5Purity:98.43% - 99.57%Color and Shape:SolidMolecular weight:447.88Elvitegravir
CAS:Controlled Product<p>Applications A novel inhibitor of human immunodeficiency virus type 1 integrase.<br>References Chou, T., et al.: Eur. J. Biochem., 115, 207 (1981), Baba, M., et al.: Antimicrob. Agents Chemother., 31, 1613 (1987), Craigie, R., et al.: J. Biol. Chem., 276, 23213 (2001), Chen, X., et al.: J. Mol. Biol., 380, 504 (2008),<br></p>Formula:C23H23ClFNO5Color and Shape:NeatMolecular weight:447.88Elvitegravir
CAS:<p>HIV-1 integrase inhibitor; inhibits DNA strand transfer</p>Formula:C23H23ClFNO5Purity:Min. 95%Color and Shape:PowderMolecular weight:477.88 g/mol
