CAS 6979-97-1

Thymidine, 3′,5′-diacetate

Description:

Thymidine, 3′,5′-diacetate is a synthetic derivative of thymidine, a nucleoside that plays a crucial role in DNA synthesis. This compound is characterized by the presence of two acetyl groups attached to the hydroxyl groups at the 3' and 5' positions of the thymidine molecule. The addition of these acetyl groups enhances the lipophilicity of the compound, which can influence its biological activity and permeability across cellular membranes. Thymidine, 3′,5′-diacetate is often utilized in biochemical research and applications, particularly in studies involving nucleic acid synthesis and modification. Its CAS number, 6979-97-1, allows for easy identification and reference in chemical databases. The compound is typically stable under standard laboratory conditions, but like many acetylated compounds, it may undergo hydrolysis in the presence of water or under alkaline conditions, reverting to its parent nucleoside. Overall, thymidine, 3′,5′-diacetate serves as an important tool in molecular biology and biochemistry, facilitating various experimental protocols.

Formula: C₁₄H₁₈N₂O₇

InChI: InChI=1S/C14H18N2O7/c1-7-5-16(14(20)15-13(7)19)12-4-10(22-9(3)18)11(23-12)6-21-8(2)17/h5,10-12H,4,6H2,1-3H3,(H,15,19,20)/t10-,11+,12+/m0/s1

InChI key: InChIKey=RGVBNBFNSBMXID-QJPTWQEYSA-N

SMILES: O=C1N([C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)C2)C=C(C)C(=O)N1

Synonyms:

• 1-(3,5-di-O-acetyl-2-deoxypentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
• 3',5'-di-O-acetylthymidine
• 3′,5′-Di-O-acetylthymidine
• 3′,5′-Diacetyl-5-methyl-2′-deoxyuridine
• 3′,5′-Diacetylthymidine
• Di-O-acetylthymidine
• NSC 526766
• NSC 67672
• Thymidine, 3′,5′-diacetate
• Thymidine 3',5'-diacetate

((2R,3S,5R)-3-Acetoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate

CAS: 6979-97-1

((2R,3S,5R)-3-Acetoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate

Purity: 98%

Molecular weight: 326.31g/mol

Ref: 54-OR1059538

3',5'-di-O-acetylthymidine

CAS: 6979-97-1

3',5'-di-O-acetylthymidine is a Nucleoside Derivative - Other modified nucleoside.

Formula: C₁₄H₁₈N₂O₇

Color and Shape: Solid

Molecular weight: 326.3

Ref: TM-TNU1395

Thymidine Impurity 2

CAS: 6979-97-1

Formula: C₁₄H₁₈N₂O₇

Molecular weight: 326.31

Ref: 4Z-T-587

3',5'-Di-O-acetylthymidine

CAS: 6979-97-1

3',5'-Di-O-acetylthymidine is a pyrimidine nucleoside that has antibacterial activity. It is an anomer of thymidine, which makes it a hydroxymethylated analog of thymine. It can be used in the preparation of uridine for the treatment of human immunodeficiency virus type 1 (HIV-1) infection and to study the mechanism of action of this nucleoside on HIV-1 replication. 3',5'-Di-O-acetylthymidine binds to the ribose moiety of pyrimidines and inhibits bacterial growth by inhibiting DNA synthesis. This compound also inhibits the growth of staphylococcus that are resistant to penicillin. The chemical structure of 3',5'-Di-O-acetylthymidine can be modified with different acetic acid substituents to produce other pyrimidine nucleosides with different antibacterial properties, such as 4-

Formula: C₁₄H₁₈N₂O₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 326.3 g/mol

Ref: 3D-ND145913

Brivudine Impurity 2

CAS: 6979-97-1

Formula: C₁₄H₁₈N₂O₇

Molecular weight: 326.31

Ref: ST-EA-CP-B132004