CAS 6980-18-3

Kasugamycin

Description:

Kasugamycin is an antibiotic compound primarily used in agriculture as a fungicide, particularly effective against various plant pathogens. It is produced by the fermentation of the bacterium *Streptomyces kasugaensis*. Kasugamycin exhibits a unique mechanism of action by inhibiting protein synthesis in sensitive organisms, which makes it effective against certain fungi and bacteria. The substance is characterized by its relatively low toxicity to humans and animals, making it a preferred choice in crop protection. Chemically, it is classified as an aminoglycoside antibiotic, and its structure includes a complex arrangement of amino sugars and a cyclic structure. Kasugamycin is soluble in water and has a moderate stability profile, which allows it to be effective in various environmental conditions. Its use is regulated in many countries, and it is important to follow guidelines to minimize the development of resistance in target organisms. Overall, kasugamycin plays a significant role in integrated pest management strategies, contributing to sustainable agricultural practices.

Formula: C₁₄H₂₅N₃O₉

InChI: InChI=1S/C14H25N3O9/c1-3-5(17-12(16)13(23)24)2-4(15)14(25-3)26-11-9(21)7(19)6(18)8(20)10(11)22/h3-11,14,18-22H,2,15H2,1H3,(H2,16,17)(H,23,24)/t3-,4+,5+,6-,7+,8+,9-,10+,11+,14-/m1/s1

InChI key: InChIKey=PVTHJAPFENJVNC-MHRBZPPQSA-N

SMILES: O([C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O)[C@@H]2[C@@H](N)C[C@H](NC(C(O)=O)=N)[C@@H](C)O2

Synonyms:

• (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl 2-amino-4-{[carboxy(imino)methyl]amino}-2,3,4,6-tetradeoxy-alpha-D-lyxo-hexopyranoside
• 3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-<span class="text-smallcaps">D</smallcap>-arabino-hexopyranosyl]-<smallcap>D</span>-chiro-inositol
• <span class="text-smallcaps">D</smallcap>-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-<smallcap>D</span>-arabino-hexopyranosyl]-
• Kasu B
• Kasumin 2L
• Kasumin 4WP
• Kasumin L
• NSC 100858
• Kasugamycin
• 3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-D-chiro-inositol
• KSM

Kasugamycin

CAS: 6980-18-3

Kasugamycin is an antibiotic that acts by binding within the mRNA channel of the 30S subunit and inhibiting protein synthesis.

Formula: C₁₄H₂₅N₃O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 379.36

Ref: TM-T2762L

Kasugamycin

CAS: 6980-18-3

Kasugamycin is an aminoglycoside antibiotic, which is derived from the actinomycete Streptomyces kasugaensis. Its mode of action involves the inhibition of protein synthesis by interfering with the function of the 30S ribosomal subunit, ultimately preventing the growth and proliferation of sensitive organisms. In agricultural contexts, Kasugamycin is primarily utilized to control bacterial and fungal diseases in a variety of crops, including rice and fruit trees. It is particularly effective against Xanthomonas oryzae, which causes bacterial leaf blight in rice, and other pathogenic organisms detrimental to plant health. The application of Kasugamycin has been an important tool for integrated pest management programs focusing on sustainable agricultural practices. As a compound with a specific mode of activity, it helps to reduce the environmental impact typically associated with broader-spectrum antibiotics, while offering target-specific disease control. Its careful application supports the minimization of resistance development, ensuring continued efficacy in protecting crop yields.

Formula: C₁₄H₂₅N₃O₉

Purity: Min. 95%

Molecular weight: 379.36 g/mol

Ref: 3D-AK183886

Kasugamycin(~70%)-13C2,15N

Controlled Product

CAS: 6980-18-3

Formula: C₂C₁₂H₂₅₁₅NN₂O₉

Color and Shape: Neat

Molecular weight: 382.342

Ref: TR-K139907