CAS: 698387-09-6 - Neratinib

Formula: C₃₀H₂₉ClN₆O₃

InChI: InChI=1S/C30H29ClN6O3/c1-4-39-28-16-25-23(15-26(28)36-29(38)9-7-13-37(2)3)30(20(17-32)18-34-25)35-21-10-11-27(24(31)14-21)40-19-22-8-5-6-12-33-22/h5-12,14-16,18H,4,13,19H2,1-3H3,(H,34,35)(H,36,38)/b9-7+

InChI key: InChIKey=JWNPDZNEKVCWMY-VQHVLOKHSA-N

SMILES: N#CC1=CN=C2C=C(OCC)C(=CC2=C1NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)NC(=O)C=CCN(C)C

Synonyms:

• (2E)-N-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
• (2E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
• (2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
• (E)-N-[4-[3-Chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
• (E)-N-[4-[[3-Chloro-4-((pyridin-2-yl)methoxy)phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)-2-butenamide
• 2-Butenamide, N-[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2E)-
• Hki-272
• Neratinib

(2E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide

CAS: 698387-09-6

• Formula: C₃₀H₂₉ClN₆O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 557.0427

Neratinib

CAS: 698387-09-6

• Formula: C₃₀H₂₉ClN₆O₃
• Color and Shape: Yellow Solid
• Molecular weight: 557.05

Neratinib

CAS: 698387-09-6

• Formula: C₃₀H₂₉ClN₆O₃
• Purity: ≥ 98.0%
• Color and Shape: White, off-white, beige or pale yellow crystalline powder
• Molecular weight: 557.04

Neratinib

CAS: 698387-09-6

• Formula: C₃₀H₂₉ClN₆O₃
• Purity: >95.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 557.05

Neratinib-d6

CAS: 1259519-18-0 698387-09-6

• Formula: C₃₀H₂₃D₆ClN₆O₃
• Molecular weight: 563.09

Neratinib

CAS: 698387-09-6

Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR …

• Formula: C₃₀H₂₉ClN₆O₃
• Purity: 100% - 98.55%
• Color and Shape: Solid
• Molecular weight: 557.04

Neratinib

CAS: 698387-09-6

• Formula: C₃₀H₂₉ClN₆O₃
• Purity: 99.9% (Typical Value in Batch COA)
• Color and Shape: pale yellow solid
• Molecular weight: 557.04g/mol

Neratinib

CAS: 698387-09-6

Applications An oral, irreversible dual EGFR/HER2 inhibitor for breast and non-small cell lung cancer. Antitumor …

• Formula: C₃₀H₂₉ClN₆O₃
• Color and Shape: Neat
• Molecular weight: 557.04

Neratinib

CAS: 698387-09-6

Irreversible ErbB receptor tyrosine kinase inhibitor

• Formula: C₃₀H₂₉ClN₆O₃
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 557.04 g/mol

Neratinib - Bio-X ™

CAS: 698387-09-6

Neratinib is a protein kinase inhibitor that is used in the treatment of breast cancer. …

• Formula: C₃₀H₂₉ClN₆O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 557.04 g/mol

Neratinib bis-N-Oxide (M11)

CAS: 698387-09-6

• Formula: C₃₀H₂₉ClN₆O₅
• Color and Shape: Neat
• Molecular weight: 589.042

Neratinib

CAS: 698387-09-6

• Purity: 99%
• Molecular weight: 557.049987792969