CAS 6989-79-3

(17R,20α,21β)-Ajmalan-17,21-diol

Description:

(17R,20α,21β)-Ajmalan-17,21-diol, with the CAS number 6989-79-3, is a naturally occurring alkaloid derived from the plant genus Rauvolfia, which is known for its medicinal properties. This compound features a complex tetracyclic structure characteristic of many indole alkaloids, specifically exhibiting a unique arrangement of functional groups that contribute to its biological activity. The presence of hydroxyl groups at the 17 and 21 positions enhances its solubility and reactivity, making it a subject of interest in pharmacological studies. Ajmalan-17,21-diol has been investigated for its potential therapeutic effects, including anti-hypertensive and anti-inflammatory properties. Its stereochemistry, indicated by the specific configuration at the 17R, 20α, and 21β positions, plays a crucial role in determining its interaction with biological targets. As with many natural products, the extraction and synthesis of this compound can be challenging, but ongoing research continues to explore its potential applications in medicine and pharmacology.

Formula: C₂₀H₂₆N₂O₂

InChI: InChI=1S/C20H26N2O2/c1-3-10-11-8-14-17-20(12-6-4-5-7-13(12)21(17)2)9-15(16(11)18(20)23)22(14)19(10)24/h4-7,10-11,14-19,23-24H,3,8-9H2,1-2H3/t10-,11+,14+,15+,16+,17+,18?,19+,20-/m1/s1

InChI key: InChIKey=CJDRUOGAGYHKKD-MUXMRKMJSA-N

SMILES: OC1[C@]23[C@]([C@]4(N5[C@@](C2)([C@@]1([C@@](C4)([C@@H](CC)[C@@H]5O)[H])[H])[H])[H])(N(C)C=6C3=CC=CC6)[H]

Synonyms:

• Isoajmaline
• 5H-6,10:11,12a-Dimethanoindolo[3,2-b]quinolizine, ajmalan-17,21-diol deriv.
• Ajmalan-17,21-diol, (17R,20α,21β)-
• Rauwolfinine
• (17R,20α,21β)-Ajmalan-17,21-diol

(+)-Isoajmaline

CAS: 6989-79-3

(+)-Isoajmaline is a natural product for research related to life sciences. The catalog number is TN4260 and the CAS number is 6989-79-3.

Formula: C₂₀H₂₆N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 326.43

Ref: TM-TN4260

(+)-Isoajmaline

CAS: 6989-79-3

(+)-Isoajmaline is a naturally occurring indole alkaloid, which is primarily sourced from the Rauwolfia plant species. This compound belongs to the class of antiarrhythmic agents, which are known for their ability to modulate the cardiac rhythm. The mode of action of (+)-Isoajmaline involves the blockade of sodium and potassium ion channels, leading to a stabilization of the cardiac membrane potential. This action results in the prolongation of the cardiac action potential duration and refractoriness, thereby helping in the control of abnormal heart rhythms.

Formula: C₂₀H₂₆N₂O₂

Purity: Min. 95%

Molecular weight: 326.40 g/mol

Ref: 3D-GAA98979