CAS 69975-86-6
:Doxofylline
Description:
Doxofylline is a xanthine derivative primarily used as a bronchodilator in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It exhibits a dual mechanism of action, functioning as both a bronchodilator and an anti-inflammatory agent. Doxofylline is characterized by its ability to relax bronchial smooth muscles, thereby improving airflow and reducing respiratory distress. Its chemical structure includes a methylxanthine core, which is responsible for its pharmacological effects. The substance is known for its favorable safety profile and lower incidence of side effects compared to other xanthine derivatives, such as theophylline. Doxofylline is typically administered orally and has a relatively long half-life, allowing for less frequent dosing. Additionally, it is often preferred in patients who may be sensitive to the side effects associated with traditional bronchodilators. Overall, doxofylline represents a valuable therapeutic option in managing obstructive airway diseases, contributing to improved patient outcomes.
Formula:C11H14N4O4
InChI:InChI=1S/C11H14N4O4/c1-13-9-8(10(16)14(2)11(13)17)15(6-12-9)5-7-18-3-4-19-7/h6-7H,3-5H2,1-2H3
InChI key:InChIKey=HWXIGFIVGWUZAO-UHFFFAOYSA-N
SMILES:C(N1C2=C(N(C)C(=O)N(C)C2=O)N=C1)C3OCCO3
Synonyms:- 1H-purine-2,6-dione, 7-(1,3-dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-
- 2-(7′-Theophyllinemethyl)-1,3-dioxolane
- 7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
- 7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
- Abc 12/3
- Abc 1213
- Ansimar
- Dioxyfilline
- Doxophylline
- Maxivent
- Synasma
- Theophylline, 7-(1,3-dioxolan-2-ylmethyl)-
- See more synonyms
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Found 12 products.
Doxofylline
CAS:Formula:C11H14N4O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:266.26Doxofylline
CAS:<p>Xanthine bronchodilator that inhibits phosphodiesterase activity</p>Formula:C11H14N4O4Molecular weight:266.25Doxofylline
CAS:Doxofylline (Doxophylline) is a methylxanthine derivative with the presence of a dioxolane group in position 7.Formula:C11H14N4O4Purity:99.958% - >99.99%Color and Shape:SolidMolecular weight:266.257-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
CAS:Formula:C11H14N4O4Purity:%Color and Shape:SolidMolecular weight:266.2533Doxofylline
CAS:Controlled Product<p>Applications Doxofylline is a xanthine molecule that appears to be both bronchodilator and anti-inflammatory with an improved therapeutic window over conventional xanthines such as Theophylline and the evidence supporting the effects of Doxofylline in the treatment of lung diseases.<br>References Franzone, J., et al.: Drugs Exp. Clin. Res., 14, 479 (1988), Nicholson, C., et al.: Pulm. Pharmacol., 7, 1 (1994), Sullivan, P., et al.: Lancet, 343, 1006 (1994),<br></p>Formula:C11H14N4O4Color and Shape:NeatMolecular weight:266.25Doxofylline - Bio-X ™
CAS:Controlled Product<p>Doxofylline is a methylxanthine derivative that is used to treat chronic obstructive pulmonary disease (COPD) and asthma. This drug’s mechanism of action is unclear however it is believed to be through inhibition of phosphodiesterase activity. As a result of this, cAMP levels are increased, promoting smooth muscle relaxation.</p>Formula:C11H14N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:266.25 g/molDoxofylline
CAS:Controlled Product<p>Phosphodiesterase inhibitor; bronchodilator</p>Formula:C11H14N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:266.25 g/mol
