CAS 69980-24-1

nicotine-methyl-D3

Description:

Nicotine-methyl-D3, identified by the CAS number 69980-24-1, is a deuterated form of nicotine, which is a naturally occurring alkaloid primarily found in tobacco plants. This compound is characterized by the substitution of hydrogen atoms with deuterium, a stable isotope of hydrogen, which enhances its utility in various scientific applications, particularly in studies involving pharmacokinetics and metabolic pathways. The presence of deuterium allows for improved tracking and analysis in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. Nicotine itself is known for its stimulant effects on the central nervous system and has implications in addiction studies. The deuterated version, while retaining the core structural and functional properties of nicotine, provides researchers with a valuable tool for investigating the behavior and interactions of nicotine in biological systems without the confounding effects of non-deuterated isotopes. Overall, nicotine-methyl-D3 serves as an important compound in both pharmacological research and the study of tobacco-related health effects.

Formula: C₁₀H₁₁D₃N₂

InChI: InChI=1/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/i1D3

SMILES: C(N1CCCC1c1cccnc1)([2H])([2H])[2H]

Nicotine-d3

CAS: 69980-24-1

Formula: C₁₀H₁₁D₃N₂

Color and Shape: Pale Yellow Liquid

Molecular weight: 165.25

Ref: 4Z-N-064

(+/-)-Nicotine-d3(N-methyl-d3)

CAS: 69980-24-1

Purity: 99 atom % D

Color and Shape: Colorless-Yellow Brown Liquid.

Molecular weight: 165.25

Ref: 3U-D3519

rac-Nicotine-d3

Controlled Product

CAS: 69980-24-1

Stability May Turn Brown on Exposure to Light or Air
Applications Labelled rac-Nicotine (N412420). Nicotine is an alkaloid isolated from plants. Nicotine is an active stimulant, having both addictive and carcinogenic properties. Nicotine can be absorbed through the alimentary canal, respiratory tract and intact skin. Nicotine is used in the treatment of smoking withdrawal syndrome. Nicotine has been used as an anthelmintic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ferretti, G., et al.: J. Med. Chem., 45, 4724 (2002), Guillen, M., et al.: J. Agric. Food Chem., 53, 1093 (2005), Ramunno, A., et al.: Bioorg. Med. Chem. Lett., 15, 3237 (2005), Alburges, M., et al.: Eur. J. Pharmacol., 573, 124 (2007),

Formula: C₁₀₂H₃H₁₁N₂

Color and Shape: Yellow

Molecular weight: 165.25

Ref: TR-N412425

(±)-Nicotine-d3

CAS: 69980-24-1

(±)-Nicotine-d3 is an indirubin analog that has shown promising anticancer activity. It acts as a kinase inhibitor, inhibiting the activity of protein kinases that are involved in cancer cell growth and proliferation. (±)-Nicotine-d3 induces apoptosis in human Chinese hamster ovary cells, which are commonly used to study the mechanisms of cancer development. This compound has been found to be effective against a wide range of tumors, including lung, breast, and prostate cancer. In addition, (±)-Nicotine-d3 can be detected in urine samples and may serve as a potential biomarker for cancer diagnosis and treatment monitoring. Overall, (±)-Nicotine-d3 is a potent inhibitor of kinases with promising anticancer properties.

Formula: C₁₀H₁₄N₂

Purity: Min. 95%

Molecular weight: 165.25 g/mol

Ref: 3D-UCA98024

rac-Nicotine-d3

CAS: 69980-24-1

Formula: C₁₀H₁₁D₃N₂

Color and Shape: Liquid

Molecular weight: 165.2500

Ref: IN-DA003U46