CAS 70-18-8

Glutathione

Description:

Glutathione, with the CAS number 70-18-8, is a tripeptide composed of three amino acids: glutamine, cysteine, and glycine. It is a crucial antioxidant found in nearly all living cells, playing a vital role in protecting cells from oxidative stress and maintaining the redox state. Glutathione exists in two forms: reduced (GSH) and oxidized (GSSG), with the reduced form being the active antioxidant. It is involved in various biochemical processes, including detoxification, protein synthesis, and the regulation of cellular functions. Glutathione is soluble in water and has a relatively low molecular weight. Its antioxidant properties are attributed to the thiol group in cysteine, which can donate electrons to neutralize free radicals. Additionally, glutathione is important in the metabolism of drugs and toxins, facilitating their excretion from the body. Deficiencies in glutathione levels have been linked to various health issues, including neurodegenerative diseases and immune dysfunction, highlighting its significance in human health and disease prevention.

Formula: C₂₀H₃₂N₆O₁₂S₂

InChI: InChI=1/C10H17N3O6S/c11-5(1-2-7(14)15)9(18)13-6(4-20)10(19)12-3-8(16)17/h5-6,20H,1-4,11H2,(H,12,19)(H,13,18)(H,14,15)(H,16,17)

InChI key: InChIKey=RWSXRVCMGQZWBV-WDSKDSINSA-N

SMILES: [C@H](C(NCC(O)=O)=O)(NC(CC[C@@H](C(O)=O)N)=O)CS

Synonyms:

• 5-L-Glutamyl-L-Cysteinylglycine
• <span class="text-smallcaps">L</smallcap>-γ-Glutamyl-<smallcap>L</span>-cysteinylglycine
• <span class="text-smallcaps">L</span>-Glutathione
• Agifutol S
• Antisense compounds
• Atomolan
• Bakezyme RX
• Copren
• Deltathione
• GSH
• Gamma-Glutamylcysteinylglycine
• Glutathion
• Glutathione reduced
• Glutathione, Reduced, Free Acid
• Glutathione-SH
• Glutation
• Glutide
• Glutinal
• Glycine, <span class="text-smallcaps">L</smallcap>-γ-glutamyl-<smallcap>L</span>-cysteinyl-
• Glycine, L-γ-glutamyl-L-cysteinyl-
• Glycine, N-(N-<span class="text-smallcaps">L</smallcap>-γ-glutamyl-<smallcap>L</span>-cysteinyl)-
• Glycine, N-(N-L-γ-glutamyl-L-cysteinyl)-
• High Thione Extract YH 15
• Isethion
• L-Glutathione
• L-Glutathione (Reduced Form)
• L-Glutathione Reduced
• L-gamma-glutamyl-3-sulfido-L-alanylglycine
• L-gamma-glutamyl-L-cysteinylglycine
• N-(N-<span class="text-smallcaps">L</smallcap>-γ-Glutamyl-<smallcap>L</span>-cysteinyl)glycine
• N-(N-L-γ-Glutamyl-L-cysteinyl)glycine
• N⁵-((R)-1-((Carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)-<span class="text-smallcaps">L</span>-glutamine
• Neuthion
• ReadiSorb
• Reduced glutathione
• ReducedGlutathione
• Tad 600
• Tathion
• Tathione
• Triptide
• gamma-L-Glutamyl-L-cysteinylglycine
• {[N-(2-ammonio-4-carboxybutanoyl)cysteinyl]amino}acetate
• γ-<span class="text-smallcaps">L</smallcap>-Glutamyl-<smallcap>L</span>-cysteinylglycine
• γ-Glutamyl-cysteinyl-glycine
• γ-Glutamylcysteinylglycine
• γ-L-Glutamyl-L-cysteinylglycine
• L-γ-Glutamyl-L-cysteinylglycine
• Glutathione
• G-L-GLUTAMYL-L-CYSTEINGLYCINE
• GAMMA-L-GLUTAMYL-L-CYSTEINYL-GLYCINE
• GAMMA-L-GLUTAMYL-CYSTEINYL GLYCINE
• GSI
• GAMMA-L-GLUTAMYL-L-CYSTEINYGLYCINE
• H-GAMMA-GLU-CYS-GLY-OH
• GLUTATHIONE REDUCED FORM
• GAMMA-GLU-CYS-GLY
• GLUTATHION (REDUCED)
• GLUTAMYLCYSTEINYLGLYCINE, REDUCED

L-Glutathione, reduced, tested to USP spec

CAS: 70-18-8

Glutathione is a tripeptide cysteine-glycine-glutamic acid which exists in cells in the reduced form (this product) or oxidised form. Reduced glutathione (GSH) is an antioxidant protecting cell components from endogenous and exogeneous reactive oxygen and nitrogen species. Reduced glutathione has also been intensely used in the affinity purification of proteins with glutathione S-transferase (GST) tag. In the protein purification process, glutathione is used for the elution of GST-fused recombinant proteins from a glutathione-immobilised resins. In the elution buffers, reduced glutathione is typically used in the 10 – 40 mM concentration range.

Formula: C₁₀H₁₇N₃O₆S

Purity: (Titration) 98.0 To 101.0%

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 307.32 g/mol

Ref: 3D-FG61468

Glutathione Reduced (GSH) extrapure, 98%

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Purity: min. 99.0%

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 307.32

Ref: SR-48938

Glutathione Reduced (GSH) ExiPlus, Multi-Compendial, 98%

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Purity: min. 98.0 - 101%

Color and Shape: White or almost white, Crystalline powder /Crystals, Clear, Colourless

Molecular weight: 307.32

Ref: SR-77285

Glutathione Reduced (GSH) for molecular biology, 99.5%

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Purity: min. 99.5%

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 307.32

Ref: SR-11514

Glutathione Reduced (GSH) for tissue culture, 99.5%

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Purity: min. 99.5 %

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 307.32

Ref: SR-16111

L-Glutathione (reduced form)

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Purity: 98.0%

Color and Shape: Powder

Molecular weight: 307.32

Ref: 10-F213215