CAS 70-22-4

Oxotremorine

Description:

Oxotremorine is a synthetic compound that acts as a muscarinic acetylcholine receptor agonist, primarily influencing the central nervous system. It is known for its ability to induce tremors and other motor effects, which makes it a useful tool in pharmacological research, particularly in studies related to Parkinson's disease and other movement disorders. The compound is characterized by its ability to mimic the action of acetylcholine, leading to increased neurotransmission in cholinergic pathways. Oxotremorine is typically used in laboratory settings and is not intended for therapeutic use in humans due to its potent effects and potential side effects. Its chemical structure includes a piperidine ring, which is common among many muscarinic agonists. As with many research chemicals, safety precautions are necessary when handling Oxotremorine, as it can have significant physiological effects. Overall, its role in neuroscience research highlights the importance of cholinergic signaling in motor control and cognitive functions.

Formula: C₁₂H₁₈N₂O

InChI: InChI=1S/C12H18N2O/c15-12-6-5-11-14(12)10-4-3-9-13-7-1-2-8-13/h1-2,5-11H2

InChI key: InChIKey=RSDOPYMFZBJHRL-UHFFFAOYSA-N

SMILES: C(C#CCN1CCCC1)N2C(=O)CCC2

Synonyms:

• 1-(2-Oxopyrrolidinyl)-4-pyrrolidinyl-2-butyne
• 1-(4-(Pirrolidin-1-Il)But-2-Inil)Pirrolidin-2-Ona
• 1-(4-(Pyrrolidin-1-Yl)But-2-Ynyl)Pyrrolidin-2-One
• 1-(4-(Pyrrolidin-1-yl)but-2-ynyl)pyrrolidin-2-on
• 1-(4-(Pyrrolidine-1-Yl)But-2-Ynil)Pyrrolidine-2-One
• 1-[4-(1-Pyrrolidinyl)-2-butyn-1-yl]-2-pyrrolidinone
• 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone
• 2'-Oxopyrrolidino-1-pyrrolidino-4-butyne
• 2-Pyrrolidinone, 1-[4-(1-pyrrolidinyl)-2-butyn-1-yl]-
• Nsc 330497
• Oxotremorin
• Oxotremorine
• Oxytremorine
• Tremorine, oxo-
• 2-Pyrrolidinone, 1-[4-(1-pyrrolidinyl)-2-butynyl]-
• 5-21-06-00370 (Beilstein Handbook Reference)
• BRN 1530948
• 2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-
• 1-[4-(pyrrolidin-1-yl)but-2-yn-1-yl]pyrrolidin-2-one
• 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidinon
• 1-[4-(Pyrrolidin-1-yl)-2-butynyl]pyrrolidin-2-one
• 1-(4-pyrrolidin-1-ylbut-2-ynyl)-2-pyrrolidone
• 1-(2-Oxopyrrolidin-1-yl)-4-(pyrrolidin-1-yl)-2-butyne

Oxotremorine

CAS: 70-22-4

Oxotremorine acts as an agonist of mAChR, specifically activating the M1 and M3 acetylcholine receptors. In drug discrimination experiments with macaques, it exhibits effects similar to nicotine.

Formula: C₁₂H₁₈N₂O

Color and Shape: Solid

Molecular weight: 206.28

Ref: TM-T203251