CAS 70-23-5

Ethyl bromopyruvate

Description:

Ethyl bromopyruvate is an organic compound with the molecular formula C5H7BrO3. It is characterized by the presence of a bromine atom attached to the pyruvate structure, which consists of a carboxylic acid and a carbonyl group. This compound typically appears as a colorless to pale yellow liquid and is known for its reactivity due to the electrophilic nature of the bromine atom. Ethyl bromopyruvate is soluble in organic solvents such as ethanol and acetone but has limited solubility in water. It is often used in organic synthesis and as a reagent in various chemical reactions, including the formation of esters and in the study of biochemical pathways. Additionally, it has garnered interest in medicinal chemistry for its potential applications in cancer research, as it can inhibit certain enzymes involved in metabolic processes. However, due to its reactivity and potential toxicity, handling ethyl bromopyruvate requires appropriate safety precautions.

Formula: C₅H₇BrO₃

InChI: InChI=1S/C5H7BrO3/c1-2-9-5(8)4(7)3-6/h2-3H2,1H3

InChI key: InChIKey=VICYTAYPKBLQFB-UHFFFAOYSA-N

SMILES: C(C(CBr)=O)(OCC)=O

Synonyms:

• 3-Bromo-2-(oxo)propionic acid ethyl ester
• 3-Bromo-2-oxopropanoic acid ethyl ester
• 3-Bromopyruvic acid ethyl ester
• Bromopiruvato De Etilo
• Bromopyruvate d'ethyle
• Bromopyruvic acid ethyl ester
• Ethyl 3-Bromo-2-Oxopropanoate
• Ethyl 3-Bromopyruvate
• Ethyl 3-bromo-2-oxopropionate
• Ethyl α-bromopyruvate
• Ethylbrompyruvat
• Nsc 62182
• Propanoic acid, 3-bromo-2-oxo-, ethyl ester
• Pyruvic acid, bromo-, ethyl ester
• Thyl 3-Bromopyruvate
• β-Bromopyruvic acid ethyl ester

Ethyl 3-bromopyruvate, tech. 75%

CAS: 70-23-5

Ethyl 3-bromopyruvate is employed in a synthesis of thioxothiazolidines from primary amines and carbon disulfide. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The origin

Formula: C₅H₇BrO₃

Purity: 75%

Color and Shape: Clear yellow to pink-red, Liquid

Molecular weight: 195.02

Ref: 02-L00582

Ethyl bromopyruvate

CAS: 70-23-5

Formula: C₅H₇BrO₃

Purity: 80%

Color and Shape: Liquid

Molecular weight: 195.0113

Ref: IN-DA0034VY

Ethyl 3-bromo-2-oxopropanoate

CAS: 70-23-5

Ethyl 3-bromo-2-oxopropanoate

Formula: C₅H₇BrO₃

Purity: tech

Color and Shape: faint yellow liquid

Molecular weight: 195.01g/mol

Ref: 54-OR015293

Ethyl bromopyruvate

CAS: 70-23-5

Formula: C₅H₇BrO₃

Purity: ≥ 80.0%

Color and Shape: Yellow liquid

Molecular weight: 195.02

Ref: 7W-GK9528

Ethyl bromopyruvate

CAS: 70-23-5

Formula: C₅H₇BrO₃

Purity: 80.0%

Color and Shape: Clear

Molecular weight: 195.012

Ref: 10-F067144

Ethyl 3-Bromopyruvate

Controlled Product

CAS: 70-23-5

Applications Ethyl 3-Bromopyruvate is used in the preparation of 1,2,4-trisubstituted imidazoles as inhibitors of growth factor-β type I ALK5 inhibitors.
References Guo, C. et al.: Bioorg. Med. Chem. Lett., 23, 5850 (2013); Catarzi, D. et al.: Farmaco, 48, 447 (1993);

Formula: C₅H₇BrO₃

Purity: >80%

Color and Shape: Neat

Molecular weight: 195.01

Ref: TR-E900540

Ethyl-3-bromopyruvate

CAS: 70-23-5

Ethyl-3-bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl-3-bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae.

Formula: C₅H₇BrO₃

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 195.01 g/mol

Ref: 3D-FE12511