CAS 70-34-8

Dinitrofluorobenzene

Description:

Dinitrofluorobenzene, with the CAS number 70-34-8, is an aromatic compound characterized by the presence of two nitro groups (-NO2) and one fluorine atom (-F) attached to a benzene ring. This compound typically appears as a yellow crystalline solid and is known for its relatively high stability under standard conditions. Dinitrofluorobenzene is primarily used in organic synthesis, particularly as a reagent for the introduction of the nitro group into other organic molecules. It exhibits moderate toxicity and can be harmful if inhaled or ingested, necessitating careful handling and appropriate safety measures. The compound is also a potent electrophile, making it useful in various chemical reactions, including nucleophilic aromatic substitution. Its reactivity and functional groups allow it to participate in a range of chemical transformations, contributing to its utility in research and industrial applications. As with many nitro compounds, it is important to consider its environmental impact and potential for degradation in various conditions.

Formula: C₆H₃FN₂O₄

InChI: InChI=1S/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H

InChI key: InChIKey=LOTKRQAVGJMPNV-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=CC(N(=O)=O)=CC=C1F

Synonyms:

• 1,3-Dinitro-4-Fluorobenzene
• 1-Fluor-2,4-dinitrobenzol
• 1-Fluoro-2,3-Dinitrobenzene
• 1-Fluoro-2,4-Dinitrobenceno
• 1-Fluoro-2,4-dinitrobenzene
• 2,4-Dinitro-1-fluorobenzene
• 2,4-Dinitro-fluorobenzene
• 2,4-Dinitrobenzene fluoride
• 2,4-Dinitrophenyl fluoride
• 2,4-Dnfb
• 4-Fluoro-1,3-dinitrobenzene
• Benzene, 1-fluoro-2,4-dinitro-
• DFB
• DNF
• Dinitrofluorobenzene
• Dnfb
• Dnp-F
• Fdnb
• Fluorodinitrobenzene
• Nsc 33519
• Sanger'S Reagent
• 2,4-Dinitrofluorobenzene

2,4-Dinitrofluorobenzene

CAS: 70-34-8

Formula: C₆H₃FN₂O₄

Purity: >99.0%(GC)

Color and Shape: White or Colorless to Yellow to Green powder to lump to clear liquid

Molecular weight: 186.10

Ref: 3B-D0835

2,4-Dinitrofluorobenzene [for HPLC Labeling]

CAS: 70-34-8

Formula: C₆H₃FN₂O₄

Purity: >99.0%(GC)

Color and Shape: White or Colorless to Yellow to Green powder to lump to clear liquid

Molecular weight: 186.10

Ref: 3B-A5512

1-Fluoro-2,4-dinitrobenzene, 99%

CAS: 70-34-8

1-Fluoro-2,4-dinitrobenzene is used to identify the amino acid sequence. It reacts with amino group of amino acids to yield dinitrophenyl-amino acids. It is also used in chromatographic methods. Further, it acts as an alkylating agent used in elucidating amino acid sequence in proteins. This Thermo

Formula: C₆H₃FN₂O₄

Purity: 99%

Color and Shape: Low melting solid or clear liquid, Yellow to orange or brown

Molecular weight: 186.10

Ref: 02-A11871

2,4-Dinitrofluorobenzene

CAS: 70-34-8

Formula: C₆H₃FN₂O₄

Purity: ≥ 98.5%

Color and Shape: Yellow to orange fused solid, or liquid

Molecular weight: 186.10

Ref: 7W-GK5333

2,4-Dinitro-1-fluorobenzene

CAS: 70-34-8

2,4-Dinitro-1-fluorobenzene

Formula: C₆H₃FN₂O₄

Purity: 97%

Color and Shape: light yellow to yellow liquid/ yellow low melting solid fused solid

Molecular weight: 186.10g/mol

Ref: 54-PC3040

2,4-Dinitrofluorobenzene

CAS: 70-34-8

Formula: C₆H₃FN₂O₄

Purity: 99.0%

Color and Shape: Solid

Molecular weight: 186.098

Ref: 10-F002693

2,4-Dinitrofluoro-Benzene

CAS: 70-34-8

Formula: C₆H₃FN₂O₄

Molecular weight: 186.10

Ref: 4Z-B-139134

2,4-Dinitrofluorobenzene

Controlled Product

CAS: 70-34-8

Applications A substituted benzene use in polypeptide sequencing (also referred to as Sanger’s reagent). Used in the derivitization of primary amines. Shown to inhibit the reductase activity of mitochondrial b-c1 complex isolated from beef heart mitochondria.
References Sanger, F. et al.: Biochem. J., 39, 507 (1945); Fariss, M.W. et al.: Methods Enzymol., 143, 101 (1987); Lorusso, M. et al.: FEBS Lett., 195, 298 (1986);

Formula: C₆H₃FN₂O₄

Color and Shape: Neat

Molecular weight: 186.1

Ref: TR-D479795

2,4-Dinitrofluorobenzene

CAS: 70-34-8

2,4-Dinitrofluorobenzene is a prodrug that is converted to the active form 2,4-dinitrophenol in vivo. It has been shown to have strong antimicrobial activity against both Gram-positive and Gram-negative bacteria. The matrix effect, which refers to the difference in solubility of a drug in different parts of the gastrointestinal tract, may affect its absorption and bioavailability. The reactive nature of 2,4-dinitrofluorobenzene may also lead to chemical reactions with other compounds in the digestive tract. This drug has been shown to be effective for bowel disease caused by allergy as well as for allergic symptoms such as urticaria and angioedema. In animal models, this drug has shown antitumor response and sesquiterpene lactone inhibitory effects on tumor cells.

Formula: C₆H₃FN₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 186.1 g/mol

Ref: 3D-FD22428

1-Fluoro-2,4-Dinitrobenzene (FDNB) for HPLC, 99%

CAS: 70-34-8

Formula: C₆H₃FN₂O₄

Molecular weight: 186.10

Ref: SR-42199

1-Fluoro-2,4-Dinitrobenzene (FDNB) extrapure AR, 99%

CAS: 70-34-8

Formula: C₆H₃FN₂O₄

Purity: min. 99%

Color and Shape: Clear, Yellow, Liquid

Molecular weight: 186.10

Ref: SR-67782