CAS 70-55-3

p-Toluenesulfonamide

Description:

p-Toluenesulfonamide, with the CAS number 70-55-3, is an organic compound characterized by its sulfonamide functional group attached to a para-substituted toluene ring. It appears as a white to off-white crystalline solid and is known for its moderate solubility in water, with better solubility in organic solvents such as ethanol and acetone. This compound is primarily used in the synthesis of pharmaceuticals and agrochemicals, serving as an intermediate in the production of various sulfonamide drugs. p-Toluenesulfonamide exhibits properties such as being a weak acid, with a pKa that allows it to act as a sulfonamide in biological systems. It is also utilized in the preparation of dyes and as a reagent in organic synthesis. Safety considerations include potential skin and eye irritation, and it should be handled with appropriate precautions in a laboratory setting. Overall, p-toluenesulfonamide is a versatile compound with significant applications in both industrial and research contexts.

Formula: C₇H₉NO₂S

InChI: InChI=1S/C7H9NO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)

InChI key: InChIKey=LMYRWZFENFIFIT-UHFFFAOYSA-N

SMILES: S(N)(=O)(=O)C1=CC=C(C)C=C1

Synonyms:

• 4-Methyl benzene sulphonamide
• 4-Methylbenzene-1-sulfonamide
• 4-Methylbenzenesulfonamide
• 4-Methylbenzensulfonamide
• 4-Methylphenylsulfonamide
• 4-Tolylsulfonamide
• Nsc 9908
• P-Toluenesulfonamide
• P-Toluolsulfonamid
• Para-Toluene Sulfonamide
• Plasticizer 15
• Toluene-4-Sulfonamide
• Toluene-4-Sulphonamide
• Tolueno-4-Sulfonamida
• Toluol-4-sulfonamid
• Tolylsulfonamide
• Topcizer 1S
• Tosylamide
• Uniplex 173
• p-Methylbenzenesulfonamide
• p-Toluene sulphonamide
• p-Tolylsulfonamide
• p-Tosylamide
• Benzenesulfonamide, 4-methyl-
• PASAM
• P-TOLUENE SULFONAMIDE
• Photoinitiator-6105l
• P-toluene Sulfonamine(PTSA)
• PTSA
• Ortho Para-Toluene Sulfonamide
• p-Toluenesulfonylamide
• p-Toluenesulphonamide
• P-toluene sulfonylamine

p-Toluenesulfonamide

CAS: 70-55-3

Formula: C₇H₉NO₂S

Purity: >98.0%(HPLC)(qNMR)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 171.21

Ref: 3B-T0281

4-Methylbenzenesulfonamide

CAS: 70-55-3

Formula: C₇H₉NO₂S

Purity: 95.0%

Color and Shape: Solid, White to almost white powder

Molecular weight: 171.21

Ref: 10-F216546

p-Toluenesulfonamide, 98+%

CAS: 70-55-3

p-Toluene sulfonamide was used to prepare the precursor required for synthesis of ethyl 6-phenyl-1-tosyl-1,2,5,6-tetrahydropyridine-3-carboxylate. It act as a derivative of ammonia activated to alkylation by alkyl halides is exemplified by the synthesis of N-tosyl-2,3-dihydroisoindole from o-xylylen

Formula: C₇H₉NO₂S

Purity: 98+%

Color and Shape: Crystals or powder or crystalline powder, White

Molecular weight: 171.21

Ref: 02-A12156

Gliclazide impurity A

CAS: 70-55-3

Gliclazide impurity A

Color and Shape: White To Off-White

Ref: 47-1304

p-Toluenesulfonamide

CAS: 70-55-3

Sulfonamides, excluding drugs

Formula: C₇H₉NO₂S

Color and Shape: White Powder

Molecular weight: 171.23 g/mol

Ref: 45-1672020

4-Methylbenzenesulfonamide

CAS: 70-55-3

Formula: C₇H₉NO₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 171.2169

Ref: IN-DA0035JC

Gliclazide EP Impurity A

CAS: 70-55-3

Formula: C₇H₉NO₂S

Color and Shape: White To Off-White Solid

Molecular weight: 171.21

Ref: 4Z-G-0513

4-Methylbenzenesulphonamide

Controlled Product

CAS: 70-55-3

Formula: C₇H₉NO₂S

Color and Shape: Neat

Molecular weight: 171.22

Ref: 86-MM0325.01

p-Toluenesulfonamide

Controlled Product

CAS: 70-55-3

Formula: C₇H₉NO₂S

Color and Shape: Neat

Molecular weight: 171.22

Ref: 04-C17594700

p-Toluenesulphonamide

CAS: 70-55-3

p-Toluenesulphonamide

Formula: C₇H₉NO₂S

Purity: 98%

Color and Shape: white crystals

Molecular weight: 171.22g/mol

Ref: 54-OR18741

p-Toluenesulfonamide

CAS: 70-55-3

Formula: C₇H₉NO₂S

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to almost white powder or crystals

Molecular weight: 171.22

Ref: 7W-GK6346

4-Tolylsulfonamide

Controlled Product

CAS: 70-55-3

Applications 4-Tolylsulfonamide is a carbonic anhydrase inhibitor used the synthesis of antiglaucoma and anticancer drugs.
References Vullo, D. et al.: Bioorg. Med. Chem. Lett., 15, 963 (2005); Vullo, D. et al.: Bioorg. Med. Chem. Lett., 15, 971 (2005);

Formula: C₇H₉NO₂S

Color and Shape: Neat

Molecular weight: 171.22

Ref: TR-T536630

Gliclazide EP Impurity A

CAS: 70-55-3

Formula: C₇H₉NO₂S

Molecular weight: 171.21

Ref: ST-EA-CP-G1001

p-Toluenesulfonamide (PTSamide) pure, 98%

CAS: 70-55-3

Formula: C₇H₉NO₂S

Purity: min. 98%

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 171.22

Ref: SR-82225

4-(Tolyl-d7)sulfonamide

Controlled Product

CAS: 70-55-3

Formula: C₇D₇H₂NO₂S

Color and Shape: Neat

Molecular weight: 178.26

Ref: TR-T536634