CAS 70020-54-1

2-chloro-8-methoxy-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine

Description:

2-Chloro-8-methoxy-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine is a chemical compound characterized by its complex structure, which includes a dibenzo[b,f][1,4]oxazepine core. This compound features a chlorine atom at the 2-position and a methoxy group at the 8-position, contributing to its unique reactivity and potential biological activity. The presence of a 4-methylpiperazine moiety at the 11-position enhances its pharmacological properties, potentially influencing its interaction with various biological targets, such as neurotransmitter receptors. The compound is likely to exhibit moderate to high lipophilicity due to its aromatic and aliphatic components, which may affect its solubility and permeability in biological systems. Additionally, the chlorine and methoxy substituents can impact its electronic properties, influencing its stability and reactivity. Overall, this compound may be of interest in medicinal chemistry, particularly in the development of therapeutic agents targeting neurological disorders.

Formula: C₁₉H₂₀ClN₃O₂

InChI: InChI=1/C19H20ClN3O2/c1-22-7-9-23(10-8-22)19-15-11-13(20)3-5-17(15)25-18-6-4-14(24-2)12-16(18)21-19/h3-6,11-12H,7-10H2,1-2H3

SMILES: CN1CCN(CC1)C1=Nc2cc(ccc2Oc2ccc(cc12)Cl)OC

Synonyms:

• 2-Chloro-8-methoxy-11-(4-methyl-1-piperazinyl)dibenzo[b,f][1,4]oxazepine

8-Methoxy Loxapine

Controlled Product

CAS: 70020-54-1

Applications A metabolite of Loxapine.
References Shen, Y., et al.: J. Biol. Chem., 268, 18200 (1993), Fiorella, D., et al.: Psychopharmacology, 121, 347 (1995), Glusa, E., and Pertz, H.: Brit. J. Pharmacol., 130, 692 (2000)

Formula: C₁₉H₂₀ClN₃O₂

Color and Shape: Neat

Molecular weight: 357.83

Ref: TR-M226150