CAS 70049-77-3

3-(Aminosulfonyl)-4-chlorobenzoyl chloride

Description:

3-(Aminosulfonyl)-4-chlorobenzoyl chloride, with the CAS number 70049-77-3, is an organic compound characterized by the presence of a benzoyl chloride functional group, which is a reactive acyl chloride. This compound features a sulfonamide group (-SO2NH2) attached to the benzene ring, specifically at the 3-position relative to the carbonyl group, and a chlorine atom at the 4-position. The presence of the aminosulfonyl group imparts unique properties, including potential reactivity in nucleophilic substitution reactions due to the electrophilic nature of the carbonyl carbon. It is typically used in organic synthesis, particularly in the preparation of sulfonamide derivatives and other pharmaceuticals. The compound is likely to be a solid at room temperature and may exhibit moderate to high solubility in polar organic solvents. Safety precautions should be observed when handling this compound, as it may be corrosive and can cause irritation to the skin and eyes. Proper storage conditions should be maintained to ensure stability and prevent degradation.

Formula: C₇H₅Cl₂NO₃S

InChI: InChI=1/C7H5Cl2NO3S/c8-5-2-1-4(7(9)11)3-6(5)14(10,12)13/h1-3H,(H2,10,12,13)

InChI key: InChIKey=SCYSJFKWFQZRJW-UHFFFAOYSA-N

SMILES: S(N)(=O)(=O)C1=CC(C(Cl)=O)=CC=C1Cl

Synonyms:

• 3-(Aminosulfonyl)-4-chlorobenzoyl chloride
• 3-(Aminosulphonyl)-4-chlorobenzoyl chloride
• 4-Chloro-3-Sulfamoylbenzoyl Chloride
• Benzoyl chloride, 3-(aminosulfonyl)-4-chloro-
• Benzoyl chloride, 4-chloro-3-sulfamoyl-
• 4-CHLORO-3-SULFAMOYL-BENZOYL CHLORIDE
• 4-Chloro-3-sulfamoyl-benzolchloride
• 4-CHLORO-3-SULFAMOYL-BENZOYL CHLORIDE 99%
• 4-CHLORO-3-SULFAMOYL-BENZOYLCHORIDE
• 4-Chloro-3-Sulfamoyl-Benzoyl

4-Chloro-3-sulfamoylbenzoyl chloride

CAS: 70049-77-3

Formula: C₇H₅Cl₂NO₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 254.0905

Ref: IN-DA00F9X5

3-(Aminosulfonyl)-4-Chlorobenzoyl Chloride

CAS: 70049-77-3

3-(Aminosulfonyl)-4-Chlorobenzoyl Chloride

Purity: 98%

Molecular weight: 254.09g/mol

Ref: 54-OR1026714

Indapamide Impurity 13 (4-Chloro-3-Sulfamoylbenzoyl Chloride)

CAS: 70049-77-3

Formula: C₇H₅Cl₂NO₃S

Color and Shape: Off-White Solid

Molecular weight: 254.08

Ref: 4Z-I-1314

4-Chloro-3-sulfamoylbenzoyl chloride

CAS: 70049-77-3

Formula: C₇H₅Cl₂NO₃S

Molecular weight: 254.08

Ref: ST-EA-CP-I21005

4-Chloro-3-sulfamoylbenzoyl Chloride (>90%)

Controlled Product

CAS: 70049-77-3

Stability Moisture Sensitive
Applications 4-Chloro-3-sulfamoylbenzoyl chloride is an intermediate used in the synthesis of indapamide, a diuretic used in the treatment of high blood pressure.
References Hoefle, M. L., et al.: J. Med. Chem., 11, 970 (1968); Wang, P., et al.: Beijing Ligong Daxue Xuebao, 21, 531 (2001); Yu, D., et al.: Huaxue Yu Shengwu Gongcheng, 24, 22 (2007); Xu, Z., et al.: Jingxi Huagong Zhongjianti, 35, 10 (2005)

Formula: C₇H₅Cl₂NO₃S

Purity: >90%

Color and Shape: Neat

Molecular weight: 254.09

Ref: TR-C428140

4-Chloro-3-sulfamoylbenzoyl chloride

CAS: 70049-77-3

Formula: C₇H₅Cl₂NO₃S

Color and Shape: Solid

Molecular weight: 254.08

Ref: 10-F496726