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CAS 70059-30-2

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Cimetidine hydrochloride

Description:
Cimetidine hydrochloride is a histamine H2 receptor antagonist primarily used to reduce stomach acid production, making it effective in treating conditions such as peptic ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. It is a white to off-white crystalline powder that is soluble in water and slightly soluble in alcohol. The chemical formula for cimetidine hydrochloride is C10H16N6S, and it has a molecular weight of approximately 252.34 g/mol. The substance acts by competitively inhibiting the binding of histamine to H2 receptors on gastric parietal cells, thereby decreasing gastric acid secretion. Cimetidine also has some anti-androgenic effects and can interact with various cytochrome P450 enzymes, leading to potential drug interactions. It is typically administered orally, and its pharmacokinetics include rapid absorption and a relatively short half-life, necessitating multiple doses throughout the day for optimal therapeutic effect. As with any medication, it is important to consider potential side effects and contraindications when prescribing or using cimetidine hydrochloride.
Formula:C10H16N6S·ClH
InChI:InChI=1S/C10H16N6S.ClH/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11;/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14);1H
InChI key:InChIKey=QJHCNBWLPSXHBL-UHFFFAOYSA-N
SMILES:C(SCCN=C(NC#N)NC)C1=C(C)N=CN1.Cl
Synonyms:
  • 1-cyano-2-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine hydrochloride (1:1)
  • 3-Cyano-2-methyl-1-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine hydrochloride
  • Aciloc
  • Biomag
  • Brumetidina
  • Cimetex
  • Cimetidine HCL
  • Guanidine, N-cyano-N′-methyl-N′′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-, hydrochloride (1:1)
  • Guanidine, N-cyano-N′-methyl-N′′-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-, monohydrochloride
  • Notul
  • See more synonyms
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Found 4 products.
  • CymitQuimica logo
    EDQM - European Pharmacopoeia
    + Info

    CIMETIDINE HYDROCHLORIDE CRS

    CAS:
    CIMETIDINE HYDROCHLORIDE CRS
    Formula:C10H17ClN6S
    Color and Shape:Crystalline Powder. White. Powder.
    Molecular weight:288.8002

    Ref: 41-C2175500

    100mg
    115.00€
  • CymitQuimica logo
    USP
    + Info

    Cimetidine Hydrochloride

    CAS:
    Compounds containing an unfused imidazole ring, whether or not hydrogenated, in the structure, nesoi
    Formula:C10H16N6S·ClH
    Color and Shape:White Off-White Powder
    Molecular weight:288.09239

    Ref: 45-1134073

  • Cimetidine hydrochloride
    Targetmol
    + Info

    Cimetidine hydrochloride

    CAS:
    Cimetidine (SKF-92334) is an oral H2 blocker with Ki 0.6 μM, anti-cancer and anti-inflammatory properties, used for ulcer research.
    Formula:C10H17ClN6S
    Color and Shape:Solid
    Molecular weight:288.8

    Ref: TM-T60584

  • Cimetidine hydrochloride
    Biosynth
    + Info

    Cimetidine hydrochloride

    CAS:
    <p>Cimetidine is a histamine-2 receptor antagonist that is used to treat peptic ulcers and gastric acid hypersecretion. It has been shown to reduce the growth of tumor cells in culture and to inhibit the synthesis of interferon alfa-2b, polymerase chain reaction (PCR) products, and carbenoxolone sodium. Cimetidine has also been shown to have a long-term toxicity in rats and mice. These effects are believed to be due to cimetidine's inhibition of plasma mass spectrometry and its ability to induce metabolic disorders such as hypokalemia, hypomagnesaemia, hypercholesterolemia, hyperglycemia, or hypothyroidism. The drug may also cause anaphylactic reactions or allergic reactions such as urticaria or angioedema. Cimetidine is not intended for injection because it is unstable when mixed with water. Famotidine is a prodrug that is</p>
    Purity:Min. 95%

    Ref: 3D-FC61521

    2g
    863.00€