CAS 700874-71-1

4-(5,6-dihydro-2-(2-pyridinyl)-4h-pyrrolo(1,2-b)pyrazol-3-yl)-7-(2-(4-morpholinyl)ethoxy)quinoline

Description:

4-(5,6-dihydro-2-(2-pyridinyl)-4H-pyrrolo(1,2-b)pyrazol-3-yl)-7-(2-(4-morpholinyl)ethoxy)quinoline, with CAS number 700874-71-1, is a complex organic compound characterized by its multi-cyclic structure, which includes a quinoline core fused with a pyrrolo-pyrazole moiety. This compound exhibits potential biological activity, often investigated for its role in medicinal chemistry, particularly in the development of therapeutic agents. The presence of the morpholine group suggests possible interactions with biological targets, enhancing its solubility and bioavailability. The compound's diverse functional groups contribute to its chemical reactivity and potential for forming various derivatives. Its synthesis typically involves multi-step organic reactions, and it may be evaluated for its pharmacological properties, including anti-cancer or anti-inflammatory activities. As with many compounds of this nature, understanding its structure-activity relationship is crucial for optimizing its efficacy and safety in potential applications.

Formula: C₂₆H₂₇N₅O₂

InChI: InChI=1S/C26H27N5O2/c1-2-9-27-22(4-1)26-25(24-5-3-11-31(24)29-26)21-8-10-28-23-18-19(6-7-20(21)23)33-17-14-30-12-15-32-16-13-30/h1-2,4,6-10,18H,3,5,11-17H2

SMILES: c1ccnc(c1)c1c(c2ccnc3cc(ccc23)OCCN2CCOCC2)c2CCCn2n1

Synonyms:

• Ly2109761
• 4-[5,6-Dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]quinoline
• LY2109761/LY-2109761
• LY210976
• 4-[2-[4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl]oxyethyl]Morpholine
• Quinoline, 4-[5,6-dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-Morpholinyl)ethoxy]-
• 7-(2-morpholinoethoxy)-4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
• LY2109761, >=98%
• 4-[5,6-Dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]quinoline LY 2109761
• 4-(2-(4-(2-(Pyridin-2-yl)-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yloxy)e

LY2109761

CAS: 700874-71-1

Formula: C₂₆H₂₇N₅O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 441.5249

Ref: IN-DA00FBJ8

LY2109761

CAS: 700874-71-1

LY2109761

Purity: ≥95%

Molecular weight: 441.52g/mol

Ref: 54-BUP12963

LY2109761

CAS: 700874-71-1

LY2109761: a TGF-β dual inhibitor, Ki=38 nM (TβRI) & 300 nM (TβRII), hinders Smad2 phosphorylation.

Formula: C₂₆H₂₇N₅O₂

Purity: 97% - 99.83%

Color and Shape: Solid

Molecular weight: 441.52

Ref: TM-T2123