CAS 70110-25-7

(2R)-2-Chloropropanoyl chloride

Description:

(2R)-2-Chloropropanoyl chloride, with the CAS number 70110-25-7, is an organic compound characterized by its acyl chloride functional group. It is a chiral molecule, with the "2R" designation indicating the specific stereochemistry at the second carbon atom. This compound typically appears as a colorless to pale yellow liquid and is known for its strong reactivity, particularly with water, alcohols, and amines, leading to the formation of corresponding acids and amides. Its reactivity is attributed to the presence of the acyl chloride group, which is a potent electrophile. The compound is used in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. Due to its reactive nature, it must be handled with care, as it can cause irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment and working in a fume hood, are essential when working with this substance.

Formula: C₃H₄Cl₂O

InChI: InChI=1S/C3H4Cl2O/c1-2(4)3(5)6/h2H,1H3/t2-/m1/s1

InChI key: InChIKey=JEQDSBVHLKBEIZ-UWTATZPHSA-N

SMILES: [C@H](C(Cl)=O)(C)Cl

Synonyms:

• (2R)-2-chloropropanoyl chloride
• (R)-2-Chloropropionyl chloride
• (2R)-2-Chloropropanoyl chloride
• (R)-2-Chloropropionyl chloride
• Propanoyl chloride, 2-chloro-, (2R)-
• Propanoyl chloride, 2-chloro-, (R)-
• Propanoyl chloride, 2-chloro-, (2R)-

(2R)-2-Chloropropanoyl chloride

CAS: 70110-25-7

(2R)-2-Chloropropanoyl chloride (CPC) is a synthetic organic compound that has been used in the Friedel-Crafts reaction. It inhibits the growth of gram-negative bacteria and is used as an antifungal to treat fungal infections. The asymmetric synthesis of CPC was achieved by using a chiral phosphoric acid catalyst, which improved the yield from 10% to 91%. Studies have shown that CPC is effective against methicillin resistant Staphylococcus aureus and various strains of Candida albicans.

Formula: C₃H₄Cl₂O

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 126.97 g/mol

Ref: 3D-FC179639