CAS 7013-07-2

(R)-(-)-4-Amino-3-hydroxybutanoic acid

Description:

(R)-(-)-4-Amino-3-hydroxybutanoic acid, commonly known as L-threonine, is an essential amino acid characterized by its aliphatic structure containing both amino and hydroxyl functional groups. It is a colorless, crystalline solid that is soluble in water, reflecting its polar nature due to the presence of the hydroxyl group. This amino acid plays a crucial role in protein synthesis and is vital for various metabolic processes in living organisms. L-threonine is involved in the production of other amino acids and is important for maintaining proper immune function and gut health. Its stereochemistry, indicated by the (R)-(-) designation, signifies its specific three-dimensional arrangement, which is critical for its biological activity. As an essential amino acid, it cannot be synthesized by the human body and must be obtained through dietary sources, particularly from protein-rich foods. In addition to its nutritional significance, L-threonine is also utilized in various industrial applications, including pharmaceuticals and animal feed.

Formula: C₄H₉NO₃

InChI: InChI=1/C4H9NO3/c5-2-3(6)1-4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m1/s1

SMILES: C([C@H](CN)O)C(=O)O

Synonyms:

• (3R)-4-Amino-3-hydroxybutanoic acid
• butanoic acid, 4-amino-3-hydroxy-, (3R)-
• (R)-4-Amino-3-Hydroxy-Butyric Acid
• (-)-β-Hydroxy-GABA
• (R)-(-)-3-Hydroxy-GABA
• R-(-)-γ-Amino-β-hydroxybutyric acid
• (R)-4-AMINO-3-HYDROXYBUTANOIC ACID
• (R)-(-)-β-Hydroxy-GABA
• (R)-4-AMINO-3-HYDROXYBUTYRIC ACID
• (R)-3-Hydroxy-4-aminobutyric acid
• L-γ-Amino-β-hydroxybutyric acid
• (R)-(-)-AMINO-3-HYDROXYBUTANOIC ACID
• BUTANOIC ACID, 4-AMINO-3-HYDROXY-, (R)
• (R)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID

(R)-(-)-Amino-3-Hydroxybutanoic Acid

CAS: 7013-07-2

Formula: C₄H₉NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 119.1192

Ref: IN-DA00FBAI

(R)-4-Amino-3-Hydroxybutanoic Acid

CAS: 7013-07-2

(R)-4-Amino-3-Hydroxybutanoic Acid

Purity: 98%

Molecular weight: 119.12g/mol

Ref: 54-OR1029363

(R)-(-)-4-Amino-3-hydroxybutanoic acid

Controlled Product

CAS: 7013-07-2

(R)-(-)-4-Amino-3-hydroxybutanoic acid is an antimicrobial agent that belongs to the class of hydroxyl-containing β-amino acids. It is a stereospecific and chemoenzymatic synthesis of (R)-(-)-4-amino-3-hydroxybutanoic acid. This compound exhibits strong antibacterial activity against Gram positive bacteria, such as Staphylococcus aureus, and has been shown to inhibit the growth of Candida albicans. (R)-(-)-4-Amino-3-hydroxybutanoic acid also inhibits the production of proteinases by various bacteria, including proteases from Staphylococcus aureus and Streptococcus faecalis.

Formula: C₄H₉NO₃

Purity: (¹H-Nmr) Min. 95.0 Area-%

Color and Shape: White Powder

Molecular weight: 119.12 g/mol

Ref: 3D-FA32147

(R)-4-Amino-3-hydroxybutanoic Acid

Controlled Product

CAS: 7013-07-2

Formula: C₄H₉NO₃

Color and Shape: Neat

Molecular weight: 119.12

Ref: TR-A611274

(R)-4-Amino-3-hydroxybutyric acid

CAS: 7013-07-2

Formula: C₄H₉NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 119.12

Ref: 10-F048077

(R)-4-Amino-3-hydroxybutyric Acid

CAS: 7013-07-2

(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.

Formula: C₄H₉NO₃

Color and Shape: Solid

Molecular weight: 119.12

Ref: TM-T85014