CAS 701917-03-5

1H-Pyrazole-3-carboxylic acid, 4-nitro-1-phenyl-

Description:

1H-Pyrazole-3-carboxylic acid, 4-nitro-1-phenyl- is an organic compound characterized by its pyrazole ring structure, which is a five-membered ring containing two nitrogen atoms. This compound features a carboxylic acid functional group (-COOH) at the 3-position and a nitrophenyl group at the 4-position, contributing to its chemical reactivity and potential applications. The presence of the nitro group (-NO2) typically enhances the compound's electrophilic character, making it useful in various chemical reactions, including nucleophilic substitutions. The phenyl group adds to the compound's hydrophobic character, influencing its solubility and interaction with biological systems. This compound may exhibit biological activity, making it of interest in medicinal chemistry and drug development. Its specific properties, such as melting point, solubility, and reactivity, would depend on the molecular interactions and the environment in which it is studied. As with many pyrazole derivatives, it may also serve as a scaffold for the synthesis of more complex molecules in pharmaceutical research.

Formula: C₁₀H₇N₃O₄

4-Nitro-1-phenyl-1H-pyrazole-3-carboxylic acid

CAS: 701917-03-5

Formula: C₁₀H₇N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 233.1803

Ref: IN-DA005KPW

4-Nitro-1-phenyl-1H-pyrazole-3-carboxylic acid

CAS: 701917-03-5

4-Nitro-1-phenyl-1H-pyrazole-3-carboxylic acid

Purity: 98%

Molecular weight: 233.18g/mol

Ref: 54-OR81525

4-Nitro-1-phenyl-1H-pyrazole-3-carboxylic acid

CAS: 701917-03-5

Formula: C₁₀H₇N₃O₄

Purity: 98%

Molecular weight: 233.183

Ref: 10-F451318

4-Nitro-1-phenyl-1H-pyrazole-3-carboxylic acid

CAS: 701917-03-5

4-Nitro-1-phenyl-1H-pyrazole-3-carboxylic acid is a potent inhibitor of the human enzyme alpha/beta hydrolase domain containing 1 (ABHD1). The inhibition is irreversible and results in the accumulation of lysophosphatidic acid (LPA) in cells. This accumulation leads to increased levels of phosphatidic acid (PA) and diacylglycerol, which are lipid signaling molecules. ABHD1 inhibitors have been shown to be efficient at inhibiting tumor cell growth in vitro and in vivo, but their potency varies widely among different compounds. 4-Nitro-1-phenyl-1H-pyrazole-3 carboxylic acid has an X-ray crystal structure that can be used as a template for designing novel inhibitors with improved physicochemical properties.

Formula: C₁₀H₇N₃O₄

Purity: Min. 95%

Molecular weight: 233.18 g/mol

Ref: 3D-BDB91703