CAS 703-61-7

2,4-dichloroquinoline

Description:

2,4-Dichloroquinoline is an organic compound characterized by its quinoline structure, which consists of a fused benzene and pyridine ring. It features two chlorine substituents at the 2 and 4 positions of the quinoline ring, contributing to its chemical reactivity and properties. This compound is typically a pale yellow to brown solid at room temperature and is sparingly soluble in water but more soluble in organic solvents such as ethanol and acetone. 2,4-Dichloroquinoline is known for its potential applications in pharmaceuticals and agrochemicals, particularly as an intermediate in the synthesis of various biologically active compounds. It exhibits antimicrobial and antifungal properties, making it of interest in medicinal chemistry. However, like many chlorinated compounds, it may pose environmental and health risks, necessitating careful handling and disposal. Its chemical formula is C9H6Cl2N, and it has a molecular weight that reflects the presence of the chlorine atoms. Safety data sheets should be consulted for specific handling and toxicity information.

Formula: C₉H₅Cl₂N

InChI: InChI=1/C9H5Cl2N/c10-7-5-9(11)12-8-4-2-1-3-6(7)8/h1-5H

SMILES: c1ccc2c(c1)c(cc(Cl)n2)Cl

Synonyms:

• Quinoline, 2,4-Dichloro-

2,4-Dichloroquinoline

CAS: 703-61-7

Formula: C₉H₅Cl₂N

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 198.05

Ref: 3B-D4452

2,4-Dichloroquinoline

CAS: 703-61-7

Formula: C₉H₅Cl₂N

Purity: 98%

Color and Shape: Solid

Molecular weight: 198.0487

Ref: IN-DA003FRR

2,4-Dichloroquinoline

CAS: 703-61-7

2,4-Dichloroquinoline

Formula: C₉H₅Cl₂N

Purity: 98%

Color and Shape: off white to faint yellow crystalline powder

Molecular weight: 198.05g/mol

Ref: 54-OR3822

2,4-Dichloroquinoline

CAS: 703-61-7

Ref: 7W-GK4220

2,4-Dichloroquinoline

Controlled Product

CAS: 703-61-7

Applications 2,4-Dichloroquinoline is used in the synthesis of tRNA synthetase inhibitors with antibacterial activity against gram-positive bacteria. Also used in the preparation of arylquinolines displaying anthelmintic properties.
References Jarvest, R. et al.: Bioorg. Med. Chem. Lett., 13, 665 (2003); Rossiter, S. et al.: Bioorg. Med. Chem. Lett., 15, 4806 (2005);

Formula: C₉H₅Cl₂N

Color and Shape: Neat

Molecular weight: 198.05

Ref: TR-D436225

2,4-Dichloroquinoline

CAS: 703-61-7

Formula: C₉H₅Cl₂N

Purity: 95%

Color and Shape: Solid

Molecular weight: 198.05

Ref: 10-F075481

2,4-Dichloroquinoline

CAS: 703-61-7

2,4-Dichloroquinoline is a chlorinated heterocyclic chemical compound. This drug is used as a monosubstituted palladium complex in organic synthesis. It can be obtained by refluxing 2,4-dichloroquinoline with hydrochloric acid, phosphorus oxychloride, and a terminal alkene in the presence of an excess of dichloromethane. The resulting chloroquine can be converted to the corresponding dichloroquinolines by treatment with acetonitrile in the presence of malonic acid. The final step is the demethylation of the quinoline ring using sodium methoxide in methanol. 2,4-Dichloroquinoline has been shown to exhibit antibacterial activity against gram-negative organisms such as Escherichia coli and Pseudomonas aeruginosa. Magnetic resonance analysis (NMR) has also been used to study its properties.

Formula: C₉H₅Cl₂N

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 198.05 g/mol

Ref: 3D-FD42902