CAS 70356-03-5
:Cefaclor monohydrate
Description:
Cefaclor monohydrate is a semisynthetic cephalosporin antibiotic, primarily used to treat bacterial infections. It is characterized by its broad-spectrum activity against various gram-positive and gram-negative bacteria. The compound is typically presented as a white to off-white crystalline powder, which is soluble in water, making it suitable for oral administration in liquid formulations. Cefaclor works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Its pharmacokinetics include good absorption from the gastrointestinal tract, with peak plasma concentrations occurring within a few hours post-administration. The monohydrate form indicates the presence of one molecule of water associated with each molecule of cefaclor, which can influence its stability and solubility. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, more severe hypersensitivity reactions. As with all antibiotics, it is essential to use cefaclor judiciously to minimize the risk of developing antibiotic resistance.
Formula:C15H14ClN3O4S·H2O
InChI:InChI=1S/C15H14ClN3O4S.H2O/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7;/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23);1H2/t9-,10-,14-;/m1./s1
InChI key:InChIKey=WKJGTOYAEQDNIA-IOOZKYRYSA-N
SMILES:O=C1N2[C@@]([C@@H]1NC([C@H](N)C3=CC=CC=C3)=O)(SCC(Cl)=C2C(O)=O)[H].O
Synonyms:- (6R,7R)-7-{[amino(phenyl)acetyl]amino}-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
- 3-chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid monohydrate
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(aminophenylacetyl)amino]-3-chloro-8-oxo-, monohydrate, [6R-[6α,7β(R*)]]-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-, hydrate (1:1), (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-aminophenylacetyl]amino]-3-chloro-8-oxo-, monohydrate, (6R,7R)-
- 7-{[Amino(Phenyl)Acetyl]Amino}-3-Chloro-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid Hydrate (1:1)
- Cefaclor monohydrate
- Cephaclor monohydrate
- Keflor
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Cefaclor Monohydrate
CAS:Formula:C15H14ClN3O4S·H2OPurity:>98.0%(HPLC)(T)Color and Shape:White to Orange to Green powder to crystalMolecular weight:385.82Cefaclor
CAS:Antibiotics nesoiFormula:C15H14ClN3O4S·H2OColor and Shape:White PowderMolecular weight:367.03935Cefaclor monohydrate
CAS:Cefaclor monohydrate (Cefaclorum) is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.Formula:C15H16ClN3O5SPurity:97.36% - 99.9%Color and Shape:White SolidMolecular weight:385.823Cefaclor, EP grade
CAS:Formula:C15H14ClN3O4S·xH2OPurity:≤ 0.5%Color and Shape:White or faintly yellow powderMolecular weight:367.81Cefaclor monohydrate
CAS:Cefaclor monohydrateFormula:C15H16ClN3O5SPurity:≥95%Color and Shape:SolidMolecular weight:385.82Cefaclor Monohydrate
CAS:Formula:C15H14ClN3O4S·H2OColor and Shape:White Or BeigeMolecular weight:385.82Cefaclor Monohydrate
CAS:Controlled ProductFormula:C15H14ClN3O4S·H2OColor and Shape:NeatMolecular weight:385.82Cefaclor Monohydrate
CAS:Formula:C15H16ClN3O5SPurity:98%Color and Shape:SolidMolecular weight:385.8226Cefaclor monohydrate
CAS:(6R,7R)-7-((R)-2-Amino-2-phenylacetamido)-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrateFormula:C15H16ClN3O5SPurity:99%Molecular weight:385.82Cefaclor Monohydrate
CAS:Controlled ProductApplications Second-generation cephalosporin antibiotic. Antibacterial.
References Gray, B.M., et al.: Antimicrob. Agents Chemother., 13, 988 (1978), Lorenz, L.J., et al.: Anal. Profiles Drug Subs., 9, 107 (1980), Hori, R., et al.: J. Pharm. Pharmacol., 40, 646 (1988),Formula:C15H14ClN3O4S·H2OColor and Shape:NeatMolecular weight:385.82Cefaclor monohydrate
CAS:Inhibitor of bacterial cell wall biogenesis; cephalosporinFormula:C15H16ClN3O5SPurity:Min. 95 Area-%Molecular weight:385.82 g/mol
