CAS 70359-46-5

Brimonidine tartrate

Description:

Brimonidine tartrate is a selective alpha-2 adrenergic agonist primarily used in ophthalmology for the treatment of glaucoma and ocular hypertension. It functions by reducing intraocular pressure through decreased aqueous humor production and increased uveoscleral outflow. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its formulation in eye drops. Its chemical structure includes a brominated phenyl ring, contributing to its pharmacological activity. Brimonidine tartrate is known for its ability to cause vasoconstriction and has neuroprotective properties, making it beneficial in managing conditions related to elevated intraocular pressure. Additionally, it may cause side effects such as ocular hyperemia and fatigue, which are important considerations in its clinical use. The compound is typically administered topically, and its efficacy is enhanced by its formulation as a tartrate salt, which improves stability and solubility. Overall, brimonidine tartrate is a vital therapeutic agent in the management of glaucoma.

Formula: C₁₁H₁₀BrN₅·C₄H₆O₆

InChI: InChI=1S/C11H10BrN5.C4H6O6/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8;5-1(3(7)8)2(6)4(9)10/h1-4H,5-6H2,(H2,15,16,17);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1

InChI key: InChIKey=QZHBYNSSDLTCRG-LREBCSMRSA-N

SMILES: BrC=1C2=C(C=CC1NC=3NCCN3)N=CC=N2.[C@@H]([C@H](C(O)=O)O)(C(O)=O)O

Synonyms:

• (5-Bromo-quinoxalin-6-yl)-(4,5-dihydro-1H-imidazol-2-yl)-amine L-tartrate
• 5-Bromo-N-(4,5-Dihydro-1H-Imidazol-2-Yl)-6-Quinoxalinamine Tartrate
• 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine 2,3-dihydroxybutanedioate (1:1)
• 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine 2,3-dihydroxybutanedioate (salt)
• 6-Quinoxalinamine, 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)
• 6-Quinoxalinamine, 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1)
• Agn 190342Lf
• Alphagan
• Alphagan P
• Brimonidine Purite
• Brimonidine tartrate
• Brominide tartrate

Brimonidine Tartrate

CAS: 70359-46-5

Color and Shape: Neat

Ref: 61-FOR1324.00

BRIMONIDINE TARTRATE CRS

CAS: 70359-46-5

BRIMONIDINE TARTRATE CRS

Formula: C₁₅H₁₄BrN₅O₆

Color and Shape: White. Slightly Yellow. Powder.

Ref: 41-Y0001658

Brimonidine Tartrate

CAS: 70359-46-5

Brimonidine Tartrate

Formula: C₁₅H₁₆BrN₅O₆

Purity: 99.4%

Color and Shape: White

Molecular weight: 441.0284

Ref: 47-1307

Brimonidine Tartrate

CAS: 70359-46-5

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi

Formula: C₁₁H₁₀BrN₅·C₄H₆O₆

Color and Shape: White Light Yellow Powder

Molecular weight: 441.0284

Ref: 45-1076400

Brimonidine L-Tartrate

CAS: 70359-46-5

Formula: C₁₁H₁₀BrN₅·C₄H₆O₆

Molecular weight: 292.14 150.09

Ref: 4Z-B-1650

5-Bromo-N-(4,5-Dihydro-1H-Imidazol-2-yl)-6-Quinoxalinamine Tartrate

CAS: 70359-46-5

5-Bromo-N-(4,5-Dihydro-1H-Imidazol-2-yl)-6-Quinoxalinamine Tartrate

Purity: 99%

Molecular weight: 442.22g/mol

Ref: 54-OR1027237

Brimonidine Tartrate

CAS: 70359-46-5

Brimonidine Tartrate

Purity: ≥98%

Molecular weight: 442.22g/mol

Ref: 54-BUP17273

Brimonidine Tartrate

CAS: 70359-46-5

Formula: C₁₁H₁₀BrN₅·C₄H₆O₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 442.23

Ref: 3B-B6383

Brimonidine Tartrate

CAS: 70359-46-5

Color and Shape: Neat

Ref: 86-MM1324.00

Brimonidine Tartrate

CAS: 70359-46-5

Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM).

Formula: C₁₅H₁₆BrN₅O₆

Purity: 99.95%

Color and Shape: Off-White Crystalline Solid

Molecular weight: 442.22

Ref: TM-T6422

Brimonidine Tartrate

CAS: 70359-46-5

Formula: C₁₁H₁₀BrN₅C₄H₆O₆

Molecular weight: 292.1 : 150.1

Ref: ST-EA-CP-B16008

Brimonidine L-Tartrate

Controlled Product

CAS: 70359-46-5

Applications It is an α2 receptor agonist. It is a drug used to treat glaucoma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Katz, L.J., et al.: Am. J. Ophthalmol., 127, 20 (1999), Cantor, L. B., Expert Opin. Pharmacother., 1, 815 (2000),

Formula: C₁₁H₁₀BrN₅·C₄H₆O₆

Color and Shape: Neat

Molecular weight: 442.22

Ref: TR-B677530

Brimonidine-d4 L-Tartrate

Controlled Product

CAS: 70359-46-5

Applications Labelled Brimonidine. It is an α2 receptor agonist. It is a drug used to treat glaucoma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Katz, L.J., et al.: Am. J. Ophthalmol., 127, 20 (1999), Cantor, L. B., Expert Opin. Pharmacother., 1, 815 (2000),

Formula: C₁₁H₆D₄BrN₅·C₄H₆O₆

Color and Shape: Neat

Molecular weight: 446.25

Ref: TR-B677533

Brimonidine-D-tartrate

CAS: 70359-46-5

Brimonidine-D-tartrate is a selective alpha-2 adrenergic agonist, which is a pharmacological compound derived synthetically, targeting specific receptor subtypes in the adrenergic receptor family. Its mode of action involves reducing aqueous humor production and increasing uveoscleral outflow in the eye, thereby lowering intraocular pressure. Additionally, it induces peripheral vasoconstriction, playing a role in reducing redness in rosacea.

Formula: C₁₅H₁₆BrN₅O₆

Color and Shape: White Powder

Molecular weight: 442.22 g/mol

Ref: 3D-FB32174