CAS 70369-47-0

2-[2-Hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]benzonitrile monohydrochloride

Description:

2-[2-Hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]benzonitrile monohydrochloride, with CAS number 70369-47-0, is a chemical compound that exhibits characteristics typical of a complex organic molecule. It features a benzonitrile core, which contributes to its aromatic properties, and includes a hydroxyl group that enhances its solubility in polar solvents. The presence of an indole moiety suggests potential biological activity, as indole derivatives are often associated with various pharmacological effects. The compound is likely to be a white to off-white solid, and its hydrochloride form indicates it is a salt, which can improve stability and solubility in aqueous solutions. The amino group in the structure may participate in hydrogen bonding, influencing its interactions with biological targets. Overall, this compound may be of interest in medicinal chemistry, particularly in the development of pharmaceuticals, due to its structural complexity and potential bioactivity.

Formula: C₂₂H₂₅N₃O₂

InChI: InChI=1/C22H25N3O2.ClH/c1-22(2,11-17-13-24-20-9-5-4-8-19(17)20)25-14-18(26)15-27-21-10-6-3-7-16(21)12-23;/h3-10,13,18,24-26H,11,14-15H2,1-2H3;1H

InChI key: InChIKey=NCEAPFRHADKEHP-UHFFFAOYSA-N

SMILES: C(C(NCC(COC1=C(C#N)C=CC=C1)O)(C)C)C=2C=3C(NC2)=CC=CC3.Cl

Synonyms:

• 2-(2-hydroxy-3-{[1-(1H-indol-3-yl)-2-methylpropan-2-yl]amino}propoxy)benzonitrile hydrochloride (1:1)
• <span class="text-smallcaps">DL</span>-Bucindolol hydrochloride
• Benzonitrile, 2-[2-hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]-, hydrochloride (1:1)
• Benzonitrile, 2-[2-hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]-, monohydrochloride
• Bucindolol hydrochloride
• Mj-13105-1
• o-[2-Hydroxy-3-[(2-indol-3-yl-1,1-dimethylethyl)amino]propoxy]benzonitrile monohydrochloride
• DL-Bucindolol hydrochloride
• MJ131051
• MJ-131051
• 2-(3-((1-(1H-indol-3-yl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)benzonitrile hydrochloride
• MJ 131051

Bucindolol hydrochloride

CAS: 70369-47-0

Bucindolol, a 4th-gen β-blocker, prevents onset AF; effectiveness varies with β₁/α(2c) genes; best in β₁389 Arg homozygotes.

Formula: C₂₂H₂₆ClN₃O₂

Color and Shape: Solid

Molecular weight: 399.91

Ref: TM-T26920

Bucindolol

CAS: 70369-47-0

Molecular weight: 363.46099853515625

Ref: 10-F493898