CAS 70371-55-0

Pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione, 5-amino-1,3-dimethyl-

Description:

Pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione, 5-amino-1,3-dimethyl- is a heterocyclic organic compound characterized by its fused pyrimidine rings and the presence of functional groups that contribute to its reactivity and biological activity. This compound typically exhibits a solid-state structure and is soluble in polar solvents, which is common for many nitrogen-containing heterocycles. The presence of amino and dimethyl groups enhances its potential for hydrogen bonding and may influence its pharmacological properties. It is often studied for its potential applications in medicinal chemistry, particularly as a scaffold for developing therapeutic agents due to its ability to interact with biological targets. The compound's CAS number, 70371-55-0, allows for precise identification in chemical databases and literature. Overall, its unique structural features and functional groups make it a subject of interest in various fields, including drug discovery and development.

Formula: C₈H₉N₅O₂

5-Amino-1,3-dimethyl-1H,2H,3H,4H-[1,3]diazino[4,5-d]pyrimidine-2,4-dione

CAS: 70371-55-0

Azelastine belongs to the class of antihistamines, and is used in the treatment of allergic diseases. It inhibits histamine release from mast cells and basophils, which are white blood cells responsible for inflammatory reactions, such as asthma and allergic rhinitis. Azelastine is not active against infections, but it is effective in the treatment of conjunctivitis caused by allergies or infection. Azelastine also has a local anesthetic effect on the eye. This drug is available in a nasal spray that can be used to treat allergic rhinitis, conjunctivitis and dermatopathy.br>
Azelastine has been shown to inhibit the growth of bacteria that are resistant to penicillin, ampicillin, erythromycin. Azelastine binds to the penicillin-binding proteins in the bacterial cell wall by competitive inhibition. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis

Formula: C₈H₉N₅O₂

Purity: Min. 95%

Molecular weight: 207.19 g/mol

Ref: 3D-VCA37155