CAS 70431-34-4

colominic acid sodium salt from E. coli

Description:

Colominic acid sodium salt, derived from Escherichia coli, is a polysaccharide composed primarily of N-acetylneuraminic acid (sialic acid) residues. It is characterized by its high molecular weight and is known for its role in the bacterial capsule, contributing to virulence and immune evasion. This compound exhibits solubility in water, making it useful in various biochemical applications. Colominic acid sodium salt is often utilized in research related to cell biology, immunology, and microbiology due to its ability to mimic glycoproteins and influence cellular interactions. Its structure allows it to participate in various biological processes, including cell signaling and pathogen-host interactions. Additionally, it has potential applications in drug delivery systems and as a component in vaccine formulations. The CAS number 70431-34-4 uniquely identifies this substance, facilitating its recognition in scientific literature and regulatory contexts. Overall, colominic acid sodium salt serves as an important tool in understanding bacterial behavior and developing therapeutic strategies.

Synonyms:

• Colominic acid sodium salt from Escherichia coli
• Colominic Acid Sodium

Colominic acid sodium salt

CAS: 70431-34-4

Formula: (C₁₁H₁₆NNaO₈)n

Purity: (HPLC)≥ 96.0%

Color and Shape: White to almost white powder

Molecular weight: 955.71

Ref: 7W-GA9667

Colominic acid sodium salt

CAS: 70431-34-4

Colominic acid sodium salt is an N-acetylneuraminic acid homopolymer produced by E coli, protein polysialylation and exhibiting antibacterial activity.

Formula: C₁₁H₁₇NNa₃O₇

Color and Shape: Solid

Molecular weight: 344.23

Ref: TM-T40814

Colominic Acid Sodium Salt from Escherichia coli

Controlled Product

CAS: 70431-34-4

Applications Colominic Acid Sodium Salt from Escherichia coli can be used as reactant/reagent for polysialic acid-based micelles for encapsulation of hydrophobic drugs.
References Bader, R. A., et al.: Biomacromolecules, 12, 314 (2011)

Formula: C₁₃H₁₉NO

Color and Shape: Neat

Molecular weight: 205.296

Ref: TR-C642503

Colominic acid sodium salt

CAS: 70431-34-4

Colominic acid (polysialic acid) is a linear small polysaccharide containing α-2,8-linked sialic acid (neurominic acid) with (n = 8 to >100) residues. Polysialic acid is an unusual post translational modification polysaccharide that is widely expressed in nature in bacterial capsules, fish, sea urchin eggs, embryonic tissues, amphibians, animal and human brains, and in a various cancers.  The major carrier of polysialic acids in mammals is the neural cell adhesion molecule (a glycoprotein that belongs to the immunoglobulin superfamily).Average molecular weight for this product is :50000-60000

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Ref: 3D-YC11298