CAS 70458-95-6

Pefloxacin mesylate

Description:

Pefloxacin mesylate is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily effective against a variety of Gram-negative and some Gram-positive bacteria, making it useful in treating various infections, particularly those of the respiratory and urinary tracts. The compound is a mesylate salt of pefloxacin, which enhances its solubility and bioavailability. Pefloxacin mesylate exhibits a mechanism of action that involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. This antibiotic is typically administered orally and is known for its relatively good tissue penetration. However, like other fluoroquinolones, it may be associated with side effects such as gastrointestinal disturbances, central nervous system effects, and potential tendon damage. It is important to use this antibiotic judiciously to minimize the risk of developing antibiotic resistance. As with any medication, its use should be guided by susceptibility patterns and clinical considerations.

Formula: C₁₇H₂₀FN₃O₃·CH₄O₃S

InChI: InChI=1S/C17H20FN3O3.CH4O3S/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21;1-5(2,3)4/h8-10H,3-7H2,1-2H3,(H,23,24);1H3,(H,2,3,4)

InChI key: InChIKey=HQQSBEDKMRHYME-UHFFFAOYSA-N

SMILES: C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(C2)N3CCN(C)CC3.S(C)(=O)(=O)O

Synonyms:

• 1-Ethyl-6-Fluoro-7-(4-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Methanesulfonate (1:1)
• 1-Ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid monomethanesulfonate
• 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, methanesulfonate (1:1)
• 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate
• 41-982Rp
• Levofloxacin Methylate
• Peflacin
• Pefloxacin Mesylate
• Pefloxacin Methane Sulphonate
• Pefloxacin methanesulfonate
• Pefloxacine Mesylate

1-Ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monomethanesulfonate

CAS: 70458-95-6

Formula: C₁₈H₂₄FN₃O₆S

Purity: 99%

Color and Shape: Solid

Molecular weight: 429.4631

Ref: IN-DA00IC2F

Pefloxacin Mesylate

CAS: 70458-95-6

Pefloxacin Mesylate (Pefloxacinium mesylate) is a synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-

Formula: C₁₈H₂₄FN₃O₆S

Purity: 99.86%

Color and Shape: Solid

Molecular weight: 429.46

Ref: TM-T0425

Pefloxacin mesylate

CAS: 70458-95-6

Pefloxacin mesylate

Purity: 98%

Molecular weight: 429.46g/mol

Ref: 54-PC108819

Pefloxacin Mesylate

CAS: 70458-95-6

Pefloxacin Mesylate

Purity: ≥98%

Molecular weight: 429.46g/mol

Ref: 54-BUP17968

Pefloxacin Mesylate

CAS: 70458-95-6

Formula: C₁₇H₂₀FN₃O₃·CH₄O₃S

Molecular weight: 333.36 96.10

Ref: 4Z-P-145008

Pefloxacin methanesulfonate

Controlled Product

CAS: 70458-95-6

Formula: C₁₇H₂₀FN₃O₃·CH₄O₃S

Color and Shape: Neat

Molecular weight: 429.46

Ref: 04-C15905000

Pefloxacin Mesylate

Controlled Product

CAS: 70458-95-6

Applications Pefloxacin is a fluorinated quinolone antibacterial; analog of Norfloxacin.
References Barre, J., et al.: J. Pharm. Sci., 73, 1379 (1984), Contrepois, A., et al.: J. Antimicrob. Chemother., 14, 51 (1984),

Formula: C₁₇H₂₀FN₃O₃·CH₄O₃S

Color and Shape: Off-White

Molecular weight: 429.46

Ref: TR-P218300

Pefloxacin mesylate

CAS: 70458-95-6

Pefloxacin mesylate is a fluoroquinolone antibiotic with action on bacterial DNA gyrase and topoisomerase IV and is used for treating bacterial infections, including urinary and respiratory tract infections.

Formula: C₁₇H₂₀FN₃O₃•CH₄O₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 429.46 g/mol

Ref: 3D-AP76653