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CAS 70459-04-0

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N-Formylnorfloxacin

Description:
N-Formylnorfloxacin is a synthetic antibacterial agent belonging to the fluoroquinolone class of antibiotics. It is characterized by its ability to inhibit bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and transcription. This compound exhibits broad-spectrum activity against various Gram-positive and Gram-negative bacteria, making it effective in treating a range of bacterial infections. N-Formylnorfloxacin is typically administered in its salt form to enhance solubility and bioavailability. Its chemical structure includes a fluorine atom, which contributes to its potency and efficacy. The substance is generally well-absorbed when taken orally, and its pharmacokinetics can be influenced by factors such as pH and the presence of food. As with other fluoroquinolones, potential side effects may include gastrointestinal disturbances, central nervous system effects, and, in rare cases, tendon damage. Due to its specific mechanism of action and side effect profile, N-Formylnorfloxacin is used judiciously in clinical settings, particularly in cases where other antibiotics may not be effective.
Formula:C17H18FN3O4
InChI:InChI=1S/C17H18FN3O4/c1-2-20-9-12(17(24)25)16(23)11-7-13(18)15(8-14(11)20)21-5-3-19(10-22)4-6-21/h7-10H,2-6H2,1H3,(H,24,25)
InChI key:InChIKey=BFGDJPQDLMOZQQ-UHFFFAOYSA-N
SMILES:C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(C2)N3CCN(C=O)CC3
Synonyms:
  • 1-Ethyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • 1-Ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
  • N-Formylnorfloxacin
  • 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-1,4-dihydro-4-oxo-
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