CAS 70476-82-3: Mitoxantrone hydrochloride

Description:Mitoxantrone hydrochloride is a synthetic anthracenedione derivative primarily used as an antineoplastic agent in the treatment of certain cancers, including breast cancer and leukemia, as well as in multiple sclerosis. It exhibits a blue color and is characterized by its ability to intercalate DNA, thereby inhibiting topoisomerase II, which disrupts DNA replication and transcription. This mechanism contributes to its cytotoxic effects on rapidly dividing cells. Mitoxantrone hydrochloride is soluble in water and exhibits a moderate lipophilicity, which influences its distribution in biological systems. The compound is typically administered intravenously and is known for its potential side effects, including cardiotoxicity, myelosuppression, and gastrointestinal disturbances. Its pharmacokinetics involve hepatic metabolism and renal excretion, necessitating careful monitoring during treatment. Overall, Mitoxantrone hydrochloride is a potent chemotherapeutic agent with specific applications and associated risks that require thorough understanding and management in clinical settings.

Formula:C₂₂H₂₈N₄O₆·2ClH

InChI:InChI=1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H

InChI key:InChIKey=ZAHQPTJLOCWVPG-UHFFFAOYSA-N

SMILES:Cl.O=C1C=2C(O)=CC=C(O)C2C(=O)C=3C(=CC=C(NCCNCCO)C13)NCCNCCO

Synonyms:
1,4-Dihydroxy-5,8-Bis({2-[(2-Hydroxyethyl)Amino]Ethyl}Amino)Anthracene-9,10-Dione Dihydrochloride
9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, dihydrochloride
9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, hydrochloride (1:2)
Bisantrone
Cl 232315
Immunex
Mitoxantrone dihydrochloride
Mitoxantrone hcl
NSC 301739
Nci 301739
See more synonyms
Novantron
Novantrone
Novatrone
Pw 3405
Mitoxantrone hydrochloride

Found 14 products.

Product data	Purity	Price range	Estimated delivery
Mitoxantrone REF: 3B-M3133CAS: 65271-80-9 70476-82-3	>95.0%(HPLC)	134.00 €~448.00 €	Tue 29 Apr 25
Mitoxantrone hydrochloride CRS REF: 41-M2305000CAS: 70476-82-3	- - -	115.00 €	Fri 02 May 25
Mitoxantrone Hydrochloride REF: 45-1445200CAS: 70476-82-3	- - -	1,367.00 €	Mon 05 May 25
Mitoxantrone dihydrochloride REF: TM-T0158CAS: 70476-82-3	100% - 99.85%	55.00 €~173.00 €	Tue 06 May 25
9,10-Anthracenedione,1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, dihydrochloride REF: IN-DA003S4UCAS: 70476-82-3	97%	52.00 €~298.00 €	Tue 06 May 25
Mitoxantrone hydrochloride REF: 54-OR1013906CAS: 70476-82-3	98%	116.00 €~1,504.00 €	Mon 05 May 25
Mitoxantrone dihydrochloride REF: 54-BUP14968CAS: 70476-82-3	≥98%	84.00 €~355.00 €	Mon 05 May 25
Mitoxantrone hydrochloride REF: 7W-GP3838CAS: 70476-82-3	- - -	To inquire	Mon 05 May 25
Mitoxantrone DiHCl REF: 4Z-M-088005CAS: 70476-82-3	- - -	To inquire	Mon 05 May 25
Mitoxantrone Dihydrochloride REF: 3B-M3110CAS: 65271-80-9 70476-82-3	>97.0%(HPLC)	60.00 €~144.00 €	Wed 07 May 25
Mitoxantrone Hydrochloride REF: 86-MM1085.00CAS: 70476-82-3	- - -	397.00 €	Wed 07 May 25
1,4-Dihydroxy-5,8-bis-[2-(2-hydroxyethylamino)ethylamino]anthraquinone dihydrochloride REF: 10-F036509CAS: 70476-82-3	97.0%	To inquire	Wed 14 May 25
Mitoxantrone Dihydrochloride REF: TR-M373426CAS: 70476-82-3	- - -	96.00 €~140.00 €	Wed 14 May 25
Mitoxantrone hydrochloride REF: 3D-FM61451CAS: 70476-82-3	Min. 97 Area-%	152.00 €~1,174.00 €	Thu 15 May 25