CymitQuimica logo

CAS 705-19-1

:

Isometronidazole

Description:
Isometronidazole is a synthetic nitroimidazole derivative primarily used as an antimicrobial agent. It exhibits broad-spectrum activity against anaerobic bacteria and certain protozoa, making it effective in treating infections such as those caused by Trichomonas vaginalis and Giardia lamblia. The compound is characterized by its nitro group, which is crucial for its biological activity, as it undergoes reduction within microbial cells to form reactive intermediates that damage DNA and inhibit nucleic acid synthesis. Isometronidazole is typically administered orally and is well-absorbed in the gastrointestinal tract. Its pharmacokinetics include a relatively short half-life, necessitating multiple doses for effective treatment. The substance is generally well-tolerated, although side effects may include gastrointestinal disturbances and, in rare cases, neurological symptoms. Due to its structural similarities to metronidazole, isometronidazole shares many of its therapeutic properties but may have different efficacy and safety profiles. As with all medications, its use should be guided by clinical considerations and susceptibility patterns of the pathogens involved.
Formula:C6H9N3O3
InChI:InChI=1S/C6H9N3O3/c1-5-7-6(9(11)12)4-8(5)2-3-10/h4,10H,2-3H2,1H3
InChI key:InChIKey=RSXWJXPKLRYMHW-UHFFFAOYSA-N
SMILES:C(CO)N1C=C(N(=O)=O)N=C1C
Synonyms:
  • 1-(2-Hydroxyethyl)-2-methyl-4-nitro-1H-imidazole
  • 1-(2-Hydroxyethyl)-2-methyl-4-nitroimidazole
  • 2-(2-Methyl-4-nitro-imidazol-1-yl)-ethanol
  • 2-(2-Methyl-4-nitroimidazol-1-yl)ethanol
  • 2-Methyl-4-nitro-1H-imidazole-1-ethanol
  • Imidazole-1-ethanol, 2-methyl-4-nitro-
  • Imidazole-1-ethanol,2-methyl-4-nitro- (7CI,8CI)
  • Isometronidazole
  • Izoklion
  • Mizonidazole
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 11 products.