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CAS 70523-31-8

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2'-deoxy-5-(trimethylsilyl)uridine

Description:
2'-Deoxy-5-(trimethylsilyl)uridine is a modified nucleoside that features a uridine base with a trimethylsilyl group attached at the 5-position of the pyrimidine ring. This modification enhances the compound's stability and solubility, making it useful in various biochemical applications, particularly in nucleic acid research and synthesis. The presence of the trimethylsilyl group can also influence the compound's reactivity and interactions with other biomolecules. As a deoxynucleoside, it lacks the hydroxyl group at the 2' position, which is characteristic of ribonucleosides, thus contributing to its unique properties in biochemical pathways. The compound is typically used in the synthesis of oligonucleotides and can serve as a building block in the development of therapeutic agents. Its CAS number, 70523-31-8, allows for easy identification and reference in chemical databases. Overall, 2'-deoxy-5-(trimethylsilyl)uridine is an important tool in molecular biology and medicinal chemistry due to its structural modifications that enhance its utility in various applications.
Formula:C12H20N2O5Si
InChI:InChI=1/C12H20N2O5Si/c1-20(2,3)9-5-14(12(18)13-11(9)17)10-4-7(16)8(6-15)19-10/h5,7-8,10,15-16H,4,6H2,1-3H3,(H,13,17,18)/t7-,8+,10+/m0/s1
Synonyms:
  • Uridine, 2'-deoxy-5-(trimethylsilyl)-
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