CAS 705263-10-1

6-bromopyrazolo[1,5-a]pyrimidine

Description:

6-Bromopyrazolo[1,5-a]pyrimidine is a heterocyclic compound characterized by its fused pyrazole and pyrimidine rings, with a bromine substituent at the 6-position of the pyrazole ring. This compound typically exhibits a pale yellow to off-white crystalline appearance. It is known for its potential biological activity, particularly in medicinal chemistry, where it may serve as a scaffold for the development of various pharmaceuticals. The presence of the bromine atom can enhance its reactivity and influence its interaction with biological targets. Additionally, 6-bromopyrazolo[1,5-a]pyrimidine may exhibit properties such as solubility in organic solvents and moderate stability under standard laboratory conditions. Its unique structure allows for various synthetic modifications, making it a valuable compound in research and drug development. As with many heterocycles, it may also participate in diverse chemical reactions, including nucleophilic substitutions and coupling reactions, further expanding its utility in synthetic organic chemistry.

Formula: C₆H₄BrN₃

InChI: InChI=1/C6H4BrN3/c7-5-3-8-6-1-2-9-10(6)4-5/h1-4H

SMILES: c1cnn2cc(cnc12)Br

Synonyms:

• Pyrazolo[1,5-A]Pyrimidine, 6-Bromo-

6-Bromopyrazolo[1,5-a]pyrimidine

CAS: 705263-10-1

Formula: C₆H₄BrN₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 198.023

Ref: 10-F049951

6-Bromopyrazolo[1,5-a]pyrimidine, 97%

CAS: 705263-10-1

6-Bromopyrazolo[1,5-a]pyrimidine is a reactant in the synthesis of LDN-212854, a selective and potent inhibitor of the BMP type I receptor kinases. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may ref

Formula: C₆H₄BrN₃

Purity: 97%

Color and Shape: Crystals or powder or crystalline powder or flakes, Pale yellow to yellow to pale orange

Molecular weight: 198.02

Ref: 02-H33855

6-Bromopyrazolo[1,5-a]pyrimidine

CAS: 705263-10-1

Formula: C₆H₄BrN₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 198.0201

Ref: IN-DA005I52

6-Bromopyrazolo[1,5-a]pyrimidine

CAS: 705263-10-1

6-Bromopyrazolo[1,5-a]pyrimidine

Formula: C₆H₄BrN₃

Purity: 97%

Color and Shape: brown solid

Molecular weight: 198.02006g/mol

Ref: 54-OR303202

6-Bromopyrazolo[1,5-a]pyrimidine

CAS: 705263-10-1

Formula: C₆H₄BrN₃

Purity: >95.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 198.02

Ref: 3B-B6505

6-Bromo-pyrazolo[1,5-a]pyrimidine

CAS: 705263-10-1

6-Bromo-pyrazolo[1,5-a]pyrimidine is a bone morphogenetic protein (BMP) inhibitor. It has been shown to be a potent inhibitor of the tyrosine kinase activity of BMP receptors and may be useful for the development of new strategies for the treatment of osteoporosis. 6-Bromo-pyrazolo[1,5-a]pyrimidine is also an effective inhibitor of the proliferation and survival of cancer cells. It inhibits cell growth by interfering with cellular signaling pathways that regulate these processes. 6-Bromo-pyrazolo[1,5-a]pyrimidine was also found to inhibit the production of bone morphogenetic protein 2 (BMP2) in mouse calvaria cells without affecting other bone metabolism markers such as alkaline phosphatase or osteocalcin.

Formula: C₆H₄BrN₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 198.02 g/mol

Ref: 3D-FB140359