CymitQuimica logo

CAS 70563-58-5

:

Herbimycin A

Description:
Herbimycin A is a natural product classified as a polyketide antibiotic, originally isolated from the bacterium Streptomyces hygroscopicus. It exhibits a complex structure characterized by a fused ring system, which contributes to its biological activity. Herbimycin A is known for its potent antitumor properties, particularly against certain types of cancer cells, and it functions primarily by inhibiting protein synthesis. The compound has garnered interest in the field of medicinal chemistry due to its unique mechanism of action and potential therapeutic applications. Additionally, Herbimycin A has been studied for its ability to interfere with cellular signaling pathways, particularly those involving tyrosine kinases, which are crucial in regulating cell growth and differentiation. Its chemical properties include solubility in organic solvents and stability under specific conditions, making it a subject of research for developing novel anticancer agents. However, further studies are necessary to fully understand its pharmacological profile and potential side effects in clinical settings.
Formula:C30H42N2O9
InChI:InChI=1/C30H42N2O9/c1-16-10-9-11-23(37-5)28(41-30(31)36)18(3)12-17(2)27(40-8)24(38-6)13-19(4)26(39-7)21-14-20(33)15-22(25(21)34)32-29(16)35/h9-12,14-15,17,19,23-24,26-28H,13H2,1-8H3,(H2,31,36)(H,32,35)/b11-9-,16-10+,18-12+/t17-,19-,23-,24-,26+,27+,28-/m0/s1
InChI key:InChIKey=MCAHMSDENAOJFZ-BVXDHVRPSA-N
SMILES:O(C)[C@H]1C=2C(=O)C(=CC(=O)C2)NC(=O)/C(/C)=C/C=C\[C@H](OC)[C@@H](OC(N)=O)\C(\C)=C\[C@H](C)[C@@H](OC)[C@@H](OC)C[C@@H]1C
Synonyms:
  • (15R)-17-Demethoxy-15-methoxy-11-O-methylgeldanamycin
  • (4E,6Z,8S,9S,10E,12S,13R,14S,16S,17R)-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
  • (8R,9R,12S,13R,14S,16S,17S)-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
  • (8S,9S,12S,13R,14S,16S,17R)-8,13,14,17-tetramethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
  • 2-Azabicyclo[16.3.1]docosane, geldanamycin deriv.
  • 8,13,14,17-Tetramethoxy-4,10,12,16-Tetramethyl-3,20,22-Trioxo-2-Azabicyclo[16.3.1]Docosa-1(21),4,6,10,18-Pentaen-9-Yl Carbamate
  • Antibiotic TAN 420F
  • Geldanamycin, 17-demethoxy-15-methoxy-11-O-methyl-, (15R)-
  • Herbimycin A
  • Herbimycin A, Streptomyces sp.
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 6 products.
  • Herbimycin A, 95%
    Alfa Aesar By Thermo Fisher Scientific
    + Info

    Herbimycin A, 95%

    CAS:
    <p>A sparingly soluble benzoquinone anti-tumor agent which interacts with the stress induced chaperone protein Hsp90 (heat shock protein 90) This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the </p>
    Formula:C30H42N2O9
    Purity:95%
    Molecular weight:574.66

    Ref: 02-J66427

    1mg
    To inquire
  • CymitQuimica logo
    Biomar
    + Info

    Herbimycin A

    CAS:
    Formula:C30H42N2O9
    Purity:91.5%
    Color and Shape:Bright yellow. Powder
    Molecular weight:574.0

    Ref: 8R-CL0085

    1mg
    To inquire
    5mg
    To inquire
  • Herbimycin A
    Apollo Scientific
    + Info

    Herbimycin A

    CAS:
    Herbimycin A
    Molecular weight:574.66g/mol

    Ref: 54-BIBR1051

    ne
    To inquire
  • Herbimycin A
    Glentham
    + Info

    Herbimycin A

    CAS:
    Formula:C30H42N2O9
    Molecular weight:574.3

    Ref: 7W-GA2466

    1mg
    865.00€
    100µg
    260.00€
  • Herbimycin A, Streptomyces Hygroscopicus
    Fluorochem
    + Info

    Herbimycin A, Streptomyces Hygroscopicus

    CAS:
    Formula:C30H42N2O9
    Purity:>98%
    Molecular weight:574.671

    Ref: 10-M01854

    1mg
    1,032.00€
  • Herbimycin
    Biosynth
    + Info

    Herbimycin

    CAS:
    <p>Herbimycin is an antibiotic, which is a natural product derived from Streptomyces bacteria. It functions primarily as a tyrosine kinase inhibitor, disrupting cellular signaling pathways by binding to the ATP-binding site of kinases and inhibiting phosphorylation events. This mode of action makes it an effective tool for scientists studying signal transduction processes and oncogenic transformation.</p>
    Formula:C30H42N2O9
    Purity:Min. 95%
    Molecular weight:574.66 g/mol

    Ref: 3D-FH75163

    1mg
    1,002.00€