CAS 7060-74-4

Oleandomycin phosphate

Description:

Oleandomycin phosphate is an antibiotic belonging to the macrolide class, primarily used for its antibacterial properties. It is derived from the fermentation of certain Streptomyces species. The compound exhibits a broad spectrum of activity against various Gram-positive bacteria and some Gram-negative organisms, making it effective in treating respiratory and skin infections. Oleandomycin phosphate is characterized by its ability to inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby interfering with the translation process. This mechanism of action is similar to that of other macrolides, such as erythromycin. The phosphate form enhances its solubility and stability in aqueous solutions, which is beneficial for pharmaceutical formulations. In terms of physical properties, oleandomycin phosphate is typically a white to off-white powder, and it is sensitive to light and moisture, necessitating proper storage conditions. As with many antibiotics, the potential for resistance development is a concern, highlighting the importance of appropriate usage in clinical settings.

Formula: C₃₅H₆₁NO₁₂·H₃O₄P

InChI: InChI=1S/C35H61NO12.H3O4P/c1-16-14-35(15-43-35)32(40)19(4)27(37)18(3)22(7)46-33(41)21(6)31(47-26-13-25(42-11)28(38)23(8)45-26)20(5)30(16)48-34-29(39)24(36(9)10)12-17(2)44-34;1-5(2,3)4/h16-31,34,37-39H,12-15H2,1-11H3;(H3,1,2,3,4)/t16-,17+,18-,19+,20+,21+,22+,23-,24-,25-,26-,27-,28-,29+,30-,31-,34-,35+;/m0./s1

InChI key: InChIKey=RLPCJGKQKFMBEI-UOBLTHIJSA-N

SMILES: P(=O)(O)(O)O.O=C1[C@]2(CO2)C[C@H](C)[C@H](O[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3)[C@@H](C)[C@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@@H](C)C(=O)O[C@H](C)[C@H](C)[C@H](O)[C@H]1C

Synonyms:

• 1,9-Dioxaspiro[2.13]hexadecane, oleandomycin deriv.
• Matromycin
• Oleandomycin Phosphate
• Oleandomycin, phosphate (1:1) (salt)

Oleandomycin Phosphate

CAS: 7060-74-4

Applications Oleandomycin Phosphate is an antibiotic substance produced by Streptomyces antibioticus no. ATCC 11891. Antibacterial.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sous, H., et al.: Arzneim.-Forsch., 8, 386 (1958); Hahn, et al.: Antibiotics, 1, 378 (1967)

Formula: C₃₅H₆₁NO₁₂·H₃O₄P

Color and Shape: White To Off-White

Molecular weight: 785.85

Ref: TR-O517505

Oleandomycin phosphate

Controlled Product

CAS: 7060-74-4

Oleandomycin phosphate is a macrolide antibiotic with action on bacterial protein synthesis inhibition and is used for treating respiratory tract infections and as a veterinary antibiotic.

Formula: C₃₅H₆₄NO₁₆P

Purity: (%) Reported (%)

Color and Shape: Powder

Molecular weight: 785.85 g/mol

Ref: 3D-AO59785

Oleandomycin Phosphate extrapure, 100U/mg

CAS: 7060-74-4

Formula: C₃₅H₆₁NO₁₂·H₃PO₄

Color and Shape: White to off-white, Powder

Molecular weight: 785.85

Ref: SR-23534