CAS 70608-72-9

5-Hydroxyeicosatetraenoic acid

Description:

5-Hydroxyeicosatetraenoic acid (5-HETE) is a bioactive lipid derived from arachidonic acid, a polyunsaturated fatty acid. It is classified as a hydroxyeicosanoid, which plays a significant role in various physiological processes, including inflammation and immune response. 5-HETE is produced through the action of lipoxygenase enzymes, specifically 5-lipoxygenase, which catalyzes the conversion of arachidonic acid into this hydroxylated derivative. The compound is known to interact with specific receptors, influencing cellular signaling pathways and contributing to the regulation of vascular tone, platelet aggregation, and leukocyte migration. Additionally, 5-HETE is involved in the modulation of pain and inflammatory responses, making it a subject of interest in pharmacological research. Its presence in biological systems is often associated with various pathological conditions, including cardiovascular diseases and inflammatory disorders. As a chemical entity, 5-HETE is characterized by its molecular structure, which includes a long hydrocarbon chain with multiple double bonds and a hydroxyl group, contributing to its reactivity and biological activity.

Formula: C₂₀H₃₂O₃

InChI: InChI=1/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+/t19-/m1/s1

InChI key: InChIKey=KGIJOOYOSFUGPC-JGKLHWIESA-N

SMILES: [C@@H](/C=C/C=C\C/C=C\C/C=C\CCCCC)(CCCC(O)=O)O

Synonyms:

• (+)-5-Hydroxyeicosatetraenoic Acid
• (5S,6E,8Z,11Z,14Z)-5-Hydroxy-6,8,11,14-eicosatetraenoic acid
• (5S,6E,8Z,11Z,14Z)-5-hydroxyicosa-6,8,11,14-tetraenoic acid
• 5(S)-Hete
• 5(S)-Hydroxy-6-trans-8,11,14-cis-eicosatetraenoic acid
• 5(S)-Hydroxyeicosatetraenoic acid
• 5-<span class="text-smallcaps">L</span>-Hydroxy-6,8,11,14-eicosatetraenoic acid
• 5-Hete
• 5-Hydroxy-6,8,11,14-eicosatetraenoic acid
• 5S-Hydroxy-6,8,11,14-(E,Z,Z,Z)-eicosatetraenoic acid
• 6,8,11,14-Eicosatetraenoic acid, 5-hydroxy-, (5S,6E,8Z,11Z,14Z)-
• 6,8,11,14-Eicosatetraenoic acid, 5-hydroxy-, [S-(E,Z,Z,Z)]-
• 5-L-Hydroxy-6,8,11,14-eicosatetraenoic acid
• 5-hydroxyeicosatetraenoicacid
• KGIJOOYOSFUGPC-JGKLHWIESA-N
• C04805
• (5Z,8Z,11Z,14Z)-5-Hydroxy-5,8,11,14-icosatetraenoic acid
• 5(S)-HETE Lipid Maps MS Standard
• 5-hydroxy-6,8,11,14-eicosatetraenoicacid
• (5S,6E,8E,11E,14E)-5-hydroxyicosa-6,8,11,14-tetraenoic acid
• 5(S)-HETE MaxSpecStandard
• (+)-5(S)-hydroxy-(6E,8Z,11Z,14Z)-*eicosatetraenoi
• (+)-5(S)-HYDROXY-(6E,8Z,11Z,14Z)-*EICOSA TETRAENOIC
• 11,14-eicosatetraenoicacid,5-hydroxy-,(s-(e,z,z,z))-8
• (+)-5-HETE, 5(S)-HETE
• (5S,6E,8Z,11Z,14Z)-5-Hydroxy-6,8,11,14-icosatetraenoic acid
• 5(S)-HYDROXYEICOSA-6E,8Z,11Z,14Z-TETRAENOIC ACID
• 5-Hydroxyeicosatetraenoate
• (+)-5(S)-HYDROXY-(6E,8Z,11Z,14Z)-EICOSATETRAENOIC ACID
• 5S-HYDROXY-6E,8Z,11Z,14Z-EICOSATETRAENOIC ACID
• 5-Hydroxyicosatetraenoic acid

5(S)-HETE

CAS: 70608-72-9

5(S)-HETE, an endogenous metabolite found in the blood, is utilized in researching Rheumatoid Arthritis, Rhinitis, and Asthma [1] [2].

Formula: C₂₀H₃₂O₃

Color and Shape: Solid

Molecular weight: 320.47

Ref: TM-T73789

5(S)-hydroxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid

CAS: 70608-72-9

Formula: C20H32O3

Purity: >98%

Color and Shape: In solution, Ethanol

Molecular weight: 320.47

Ref: 48-14-2081

5-Hydroxy-6,8,11,14-eicosatetraenoic acid

CAS: 70608-72-9

Please enquire for more information about 5-Hydroxy-6,8,11,14-eicosatetraenoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₀H₃₂O₃

Purity: Min. 95%

Molecular weight: 320.5 g/mol

Ref: 3D-VCA60872