CAS 70643-23-1

8-Chloro-1-(4-hydroxyphenyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione

Description:

8-Chloro-1-(4-hydroxyphenyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione, with the CAS number 70643-23-1, is a synthetic compound belonging to the benzodiazepine class, which is known for its psychoactive properties. This substance features a benzodiazepine core structure, characterized by a fused benzene and diazepine ring, with a chlorine atom at the 8-position and a hydroxyphenyl group at the 1-position. The presence of the hydroxy group contributes to its potential biological activity, possibly influencing its interaction with neurotransmitter systems. The compound is typically studied for its pharmacological effects, which may include anxiolytic, sedative, or anticonvulsant properties. Its chemical stability, solubility, and reactivity can vary based on environmental conditions and the presence of other substances. As with many benzodiazepines, safety and toxicity profiles are crucial for understanding its therapeutic potential and risks. Proper handling and usage in research or clinical settings are essential to mitigate any adverse effects associated with its pharmacological activity.

Formula: C₁₅H₁₁ClN₂O₃

InChI: InChI=1S/C15H11ClN2O3/c16-9-1-6-12-13(7-9)18(15(21)8-14(20)17-12)10-2-4-11(19)5-3-10/h1-7,19H,8H2,(H,17,20)

InChI key: InChIKey=CVYAYORYXFSRGC-UHFFFAOYSA-N

SMILES: O=C1N(C=2C(NC(=O)C1)=CC=C(Cl)C2)C3=CC=C(O)C=C3

Synonyms:

• 4′-Hydroxy-N-demethylclobazam
• M 5
• 8-Chloro-1-(4-hydroxyphenyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
• M 5 (clobazam metabolite)
• 1H-1,5-Benzodiazepine-2,4(3H,5H)-dione, 8-chloro-1-(4-hydroxyphenyl)-

4'-Hydroxy-N-desmethylclobazam

Controlled Product

CAS: 70643-23-1

Applications 4'-Hydroxy-N-desmethylclobazam is used to study inhibitory effect of stiripentol on clobazam metabolism.
References Giraud, C., et al.: Drug Metab. Dispos., 34, 608 (2006);

Formula: C₁₅H₁₁ClN₂O₃

Color and Shape: Neat

Molecular weight: 302.71

Ref: TR-C582505