CAS 7075-11-8

cytosine B-D-arabinofuranoside*5'-monophosphate F

Description:

Cytosine B-D-arabinofuranoside 5'-monophosphate F, commonly referred to by its CAS number 7075-11-8, is a nucleoside analog that plays a significant role in molecular biology and pharmacology. This compound is a derivative of cytosine, one of the four primary nucleobases in DNA and RNA, and features an arabinofuranosyl sugar moiety. Its structure includes a phosphate group attached at the 5' position, which is crucial for its function in nucleic acid synthesis and metabolism. Cytosine B-D-arabinofuranoside 5'-monophosphate F is known for its potential antiviral and anticancer properties, as it can interfere with nucleic acid synthesis in rapidly dividing cells. The compound is typically used in research settings to study cellular processes and the mechanisms of action of various therapeutic agents. Its solubility and stability in biological systems make it a valuable tool in the development of nucleoside-based drugs. Overall, this compound exemplifies the intersection of chemistry and biology in the quest for effective therapeutic strategies.

Formula: C₉H₁₄N₃O₈P

InChI: InChI=1/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7+,8-/m1/s1

Synonyms:

• Ara-5'-CMP
• 1-beta-D-Arabinofuranosylcytosine 5'-monophosphate
• 1-beta-D-Arabinofuranosylcytosine 5'-phosphate
• 1beta-Arabino-furanosylcytosine-5'-monophosphoric acid, D-
• Arabinosylcytosine 5'-monophosphate
• Aracytidine 5'-monophosphate
• Aracytidine 5'-phosphate
• Cytarabine 5'-monophosphate
• Cytosine arabinoside 5'-monophosphate
• Cytosine arabinoside 5'-phosphate
• Cytosine arabinoside 5'MP
• Cytosine arabinoside monophosphate
• Nsc 99445
• 2(1H)-Pyrimidinone, 4-amino-1-(5-O-phosphono-beta-D-arabinofuranosyl)-
• Cytosine, 1-beta-D-arabinofuranosyl-, 5'-(dihydrogen phosphate) (8CI)
• 4-amino-1-(5-O-phosphono-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
• 1-β-D-Arabinofuranosylcytosine 5'-monophosphate
• 4-AMino-1-(5-O-phosphono-β-D-arabinofuranosyl)-
• CYTOSINE BETA-D-ARABINOFURANOSIDE 5'-MONOPHOSPHATE
• cytosine B-D-arabinofuranoside*5'-monophosphate F
• ARA-CMP
• 4-Amino-1-(5-O-phosphono-β-D-arabinofuranosyl)-1,2-dihydropyrimidin-2-one
• [(2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
• ((2R,3S,4S,5R)-5-(4-AMino-2-oxopyriMidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl dihydrogen phosphate
• cytosine β-d-arabinofuranoside 5'-monophosphate
• 4-Amino-1-[5-O-(dihydroxyphosphinyl)-β-D-arabinofuranosyl]pyrimidine-2(1H)-one
• 1-beta-d-arabinofuranosylcytosine5’-monophosphate
• ((2R,3S,4S,5R)
• CYTOSINE B-D-ARABINOFURANOSIDE5'-MONOPHO SPHATE FRE
• Cytarabine Monophosphate
• 4-Amino-1-(5-O-phosphono--D-arabinofuranosyl)-2(1H)-pyrimidinone
• Cytarabine Impurity 8
• 1--D-Arabinofuranosylcytosine 5'-Monophosphate
• Cytarabine 5a€-Monophosphate
• 5'-Monophosphate cytosine arabiniside
• 1-(2-Oxo-1,2-dihydro-4-aminopyrimidine-1-yl)-1-deoxy-β-D-arabinofuranose 5-phosphoric acid
• Cytosine--D-arabinofuranoside-5'-monophosphoric Acid
• 1-β-D-adenosineabinofuranosylcytosine-5'-monophosphate
• 2(1H)-Pyrimidinone, 4-amino-1-(5-O-phosphono-β-D-arabinofuranosyl)-
• 2(1H)-Pyrimidinone,4-amino-1-(5-O-phosphono-b-D-arabinofuranosyl)-
• Cytosine-beta-D-arabinofuranoside-5zzhlxy-monophosphate

2(1H)-Pyrimidinone, 4-amino-1-(5-O-phosphono-b-D-arabinofuranosyl)-

CAS: 7075-11-8

Formula: C₉H₁₄N₃O₈P

Purity: 98%

Color and Shape: Solid

Molecular weight: 323.1965

Ref: IN-DA00IC3K

Cytosine-β-D-arabinofuranoside-5''-monophosphate

CAS: 7075-11-8

Formula: C₉H₁₄N₃O₈P

Purity: ≥ 99.0%

Color and Shape: White to off-white powder

Molecular weight: 323.20

Ref: 7W-GE8537

Cytarabine Monophosphate

CAS: 7075-11-8

Formula: C₉H₁₄N₃O₈P

Molecular weight: 323.20

Ref: 4Z-C-150003

Cytarabine-13C3 5’-Monophosphate

Controlled Product

CAS: 7075-11-8

Stability Hygroscopic
Applications A labelled derivative of Cytarabine, a potent cytotoxic-antiviral nucleoside.
References Kufe, D., et al.: J. Biol. Chem., 255, 8997 (1980), Ross, D., et al.: Cancer Res., 50, 2658 (1990), Bhalla, K., et al.: Blood, 80, 2883 (1992), Tonetti, D., et al.: J. Biol. Chem., 269, 23230 (1994),

Formula: C₆C₃H₁₄N₃O₈P

Color and Shape: Neat

Molecular weight: 326.17

Ref: TR-C998107

Cytarabine 5’-Monophosphate

Controlled Product

CAS: 7075-11-8

Stability Hygroscopic, Unstable in Solution
Applications A derivative of Cytarabine, a potent cytotoxic-antiviral nucleoside.
References Kufe, D., et al.: J. Biol. Chem., 255, 8997 (1980), Ross, D., et al.: Cancer Res., 50, 2658 (1990), Bhalla, K., et al.: Blood, 80, 2883 (1992), Tonetti, D., et al.: J. Biol. Chem., 269, 23230 (1994),

Formula: C₉H₁₄N₃O₈P

Color and Shape: Neat

Molecular weight: 323.20

Ref: TR-C998105

1-(β-D-Arabinofuranosyl)cytosine 5'-monophosphate

CAS: 7075-11-8

1-(β-D-Arabinofuranosyl)cytidine 5'-monophosphate (ara-CMP) is a nucleotide derivative of cytidine, specifically a nucleotide where the ribose sugar is replaced by the arabinose sugar. It's a pyrimidine nucleotide commonly known as Cytarabine 5'-monophosphate or arabinosylcytosine 5'-monophosphate.

Formula: C₉H₁₄N₃O₈P

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 323.2 g/mol

Ref: 3D-NA10080

Cytarabine 5′-monophosphate

CAS: 7075-11-8

Cytarabine 5′-monophosphate (ara-CMP), an active metabolite of the nucleoside analog cytarabine formed by deoxycytidine kinase, is incorporated into DNA by DNA polymerase α, significantly slowing DNA synthesis. It inhibits nuclear and mitochondrial DNA replication in S. cerevisiae at 15 mM and improves survival in an L1210 murine leukemia model at 3.5-75.1 mg/kg.

Formula: C₉H₁₄N₃O₈P

Color and Shape: Solid

Molecular weight: 323.198

Ref: TM-T84932