CAS 7076-23-5

(R)-Nornicotine

Description:

(R)-Nornicotine is an alkaloid derived from the tobacco plant, specifically a minor metabolite of nicotine. It is characterized by its chiral nature, possessing a specific stereochemistry that influences its biological activity. The compound has a molecular formula that reflects its nitrogen-containing structure, which is typical of many alkaloids. (R)-Nornicotine exhibits a range of pharmacological effects, primarily acting as a nicotinic acetylcholine receptor agonist, which can influence neurotransmission and potentially affect behaviors related to addiction and cognition. Its solubility properties are consistent with other alkaloids, often being soluble in organic solvents while having limited solubility in water. The compound is of interest in both pharmacological research and toxicology, as it may contribute to the effects of tobacco consumption. Additionally, its presence in tobacco products raises questions regarding its role in the overall toxicity and addictive potential of nicotine-containing substances. As with many alkaloids, safety and handling precautions are necessary due to its biological activity.

Formula: C₉H₁₂N₂

InChI: InChI=1S/C9H12N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5,7,9,11H,2,4,6H2/t9-/m1/s1

InChI key: InChIKey=MYKUKUCHPMASKF-SECBINFHSA-N

SMILES: [C@@H]1(CCCN1)C=2C=CC=NC2

Synonyms:

• (+)-1′-Demethylnicotine
• (+)-2-(3′-Pyridyl)pyrrolidine
• (+)-Nornicotine
• (R)-(+)-Nornicotine
• 3-(2R)-2-Pyrrolidinylpyridine
• 3-[(2R)-pyrrolidin-2-yl]pyridine
• Nicotine, 1′-demethyl-, (+)-
• Nornicotine, hydrochloride, (-)-
• Pyridine, 3-(2-pyrrolidinyl)-, (R)-
• Pyridine, 3-(2R)-2-pyrrolidinyl-
• d-Nornicotine
• l-Nornicotine hydrochloride

(R)-3-(Pyrrolidin-2-yl)pyridine

CAS: 7076-23-5

Formula: C₉H₁₂N₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 148.2050

Ref: IN-DA00FH9F

(R)-3-(pyrrolidin-2-yl)pyridine

CAS: 7076-23-5

(R)-3-(pyrrolidin-2-yl)pyridine

Purity: 98%

Molecular weight: 148.20g/mol

Ref: 54-OR87849

(R)-Nornicotine

Controlled Product

CAS: 7076-23-5

Applications (R)-Nornicotine a metabolite of Nicotine (N412420). It can be used for the preparation of Nicotinoids, used as an insecticide.
References Wynder, E.L., et al.: Tobacco and Tobacco Smoke, Studies in Experimental Carcinogenesis Academic Press, Inc., New York, 377 (1968); Kool, J., et al.: J. Med. Chem., 49, 3287 (2006); Kool, J., et al.: Drug Metab. Dispos., 35, 640 (2007)

Formula: C₉H₁₂N₂

Color and Shape: Yellow To Dark Orange

Molecular weight: 148.2

Ref: TR-N757005

(R)-3-(Pyrrolidin-2-yl)pyridine

CAS: 7076-23-5

Formula: C₉H₁₂N₂

Purity: 98%

Molecular weight: 148.209

Ref: 10-F445644