CAS 70778-75-5

3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate

Description:

3-(Hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, with CAS number 70778-75-5, is a synthetic phospholipid compound characterized by its amphiphilic nature, which includes both hydrophilic and hydrophobic regions. This molecule features a glycerol backbone esterified with long-chain fatty acids, specifically hexadecanoyl and octadec-9-enoyl groups, contributing to its lipid solubility. The presence of a trimethylammonio group imparts a positive charge, enhancing its interaction with negatively charged biological membranes and facilitating its role in membrane dynamics and cellular processes. This compound is often utilized in biochemistry and pharmaceutical applications, particularly in drug delivery systems and the formulation of liposomes. Its unique structure allows it to form micelles or bilayers in aqueous environments, making it valuable for encapsulating hydrophobic drugs or enhancing the solubility of various compounds. Overall, its characteristics make it a significant molecule in the study of membrane biology and drug formulation technologies.

Formula: C₄₂H₈₂NO₈P

InChI: InChI=1/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-

SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)OC(COC(=O)CCCCCCCCCCCCCCC)COP(=O)([O-])OCC[N+](C)(C)C

Synonyms:

• ethanaminium, 2-[[hydroxy[3-[(1-oxohexadecyl)oxy]-2-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propoxy]phosphinyl]oxy]-N,N,N-trimethyl-, inner salt

1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine-13C18

Controlled Product

CAS: 70778-75-5

Applications Labelled glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.
References Perides, G., et al.: J. Biol. Chem., 262, 13742 (1987),

Formula: C₂₄₁₃C₁₈H₈₂NO₈P

Color and Shape: Neat

Molecular weight: 777.94

Ref: TR-P161003

1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine-13C16 (Contained up to 2% unlabeled)

Controlled Product

CAS: 70778-75-5

Stability Hygroscopic
Applications Labelled glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.
References Perides, G., et al.: J. Biol. Chem., 262, 13742 (1987),

Formula: C₂₆₁₃C₁₆H₈₂NO₈P

Color and Shape: Neat

Molecular weight: 775.96

Ref: TR-P161002

1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine

CAS: 70778-75-5

1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (POPC) is a phospholipid that has been shown to have the ability to inhibit the growth of bacteria. POPC is an amphiphilic molecule with hydrophobic and hydrophilic properties, which allows it to form micelles in aqueous environments, thereby increasing its antimicrobial activity. The lipid chains are composed of saturated and unsaturated fatty acids, which confer POPC with thermal expansion properties. These properties allow POPC to be used as a matrix for drug delivery systems, as well as an experimental model for studying metabolic disorders such as hepatic steatosis.

Formula: C₄₂H₈₃NO₈P

Purity: Min. 95%

Molecular weight: 761.08 g/mol

Ref: 3D-FP26731