CAS 708-79-2

1-Methyluric acid

Description:

1-Methyluric acid, with the CAS number 708-79-2, is a derivative of uric acid, characterized by the presence of a methyl group at the nitrogen atom in the uric acid structure. This compound is a purine derivative and is part of the broader category of nucleobases and nucleotides, which are essential for various biological processes. It typically appears as a white to off-white crystalline solid and is soluble in water, reflecting its polar nature due to the presence of multiple functional groups, including carboxylic acid and amine groups. 1-Methyluric acid is of interest in biochemical research, particularly in studies related to purine metabolism and its potential implications in various physiological and pathological conditions. Its biological activity and interactions with enzymes involved in purine metabolism can provide insights into metabolic disorders. As with many organic compounds, it is important to handle 1-methyluric acid with care, following appropriate safety protocols to mitigate any potential health risks associated with exposure.

Formula: C₆H₆N₄O₃

InChI: InChI=1S/C6H6N4O3/c1-10-4(11)2-3(9-6(10)13)8-5(12)7-2/h1H3,(H,9,13)(H2,7,8,12)

InChI key: InChIKey=QFDRTQONISXGJA-UHFFFAOYSA-N

SMILES: O=C1C2=C(NC(=O)N1C)NC(=O)N2

Synonyms:

• 1-Methyl-1H-purine-2,6,8(3H,7H,9H)-trione
• 1-Methyl-2,3,6,7,8,9-hexahydro-1H-purine-2,6,8-trione
• 1-Methyl-7,9-dihydro-3H-purine-2,6,8-trione
• 1-methyl-7,9-dihydro-1H-purine-2,6,8(3H)-trione
• 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-1-methyl-
• 7,9-Dihydro-1-methyl-1H-purine-2,6,8(3H)-trione
• N¹-Methyluric acid
• Uric acid, 1-methyl-
• N1-Methyluric acid
• 1-Methyluric acid

1-Methyl-1H-purine-2,6,8(3H,7H,9H)-trione

CAS: 708-79-2

Formula: C₆H₆N₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 182.1368

Ref: IN-DA003EJ1

1-Methyluric acid

CAS: 708-79-2

1-Methyluric acid

Purity: ≥98%

Molecular weight: 182.14g/mol

Ref: 54-BUP08050

Theophylline Impurity 17

CAS: 708-79-2

Formula: C₆H₆N₄O₃

Molecular weight: 182.14

Ref: 4Z-T-6027

1-Methyluric Acid

Controlled Product

CAS: 708-79-2

Applications A metabolite of Theophylline.
References Chen, Y., et al.: Clin. Exper. Pharmacol. Physiol., 36, 828 (2009), Yu, C., et al.: J. Bacteriol., 191, 4624 (2009), Jetter, A., et al.: Eur. J. Clin. Pharmacol., 65, 411 (2009),

Formula: C₆H₆N₄O₃

Color and Shape: Light Yellow To Light Brown

Molecular weight: 182.14

Ref: TR-M338180

1-Methyluric acid

Controlled Product

CAS: 708-79-2

1-Methyluric acid is a purine derivative that is a metabolite of caffeine. It is formed by the hepatic cytochrome P450 enzyme system and excreted in the urine. 1-Methyluric acid has been shown to be metabolized by rat liver microsomal enzymes, with the production of malonic acid, which may be responsible for its observed hepatotoxicity. The drug has also been shown to have an antibody response in rats and has been found to inhibit the activity of human liver enzymes. It also inhibits rat kidney enzyme activities and causes renal toxicity in rats. There are many drug interactions that can occur with 1-methyluric acid, including those with warfarin, phenytoin, carbamazepine, and diazepam. This drug should not be used in patients with severe renal impairment or chronic renal failure because it can cause acute renal failure due to its high degree of protein binding and rapid elimination from the body.

Formula: C₆H₆N₄O₃

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 182.14 g/mol

Ref: 3D-FM08042

1-Methyluric acid

CAS: 708-79-2

1-Methyluric acid (1-Methylurate) acts on the bladder mucosa and increases the levels of insulin, triglycerides, cholesterol, and blood glucose.

Formula: C₆H₆N₄O₃

Purity: 98.05%

Color and Shape: Solid

Molecular weight: 182.14

Ref: TM-T10020

Theophylline Impurity 17

CAS: 708-79-2

Formula: C₆H₆N₄O₃

Molecular weight: 182.14

Ref: ST-EA-CP-T59046