CAS 70805-85-5

DESOGESTREL RELATED COMPOUND B (15 MG) (3-HYDROXY-DESOGESTREL)

Description:

Desogestrel Related Compound B, also known as 3-Hydroxy-Desogestrel, is a synthetic progestin with a chemical structure closely related to desogestrel, which is commonly used in hormonal contraceptives. This compound is characterized by its hydroxyl group at the C3 position, which differentiates it from desogestrel. It exhibits progestogenic activity, meaning it can mimic the effects of the natural hormone progesterone in the body. The compound is typically administered in milligram doses and is known for its role in regulating menstrual cycles and preventing ovulation. Its pharmacological properties include the ability to bind to progesterone receptors, influencing various physiological processes such as endometrial stabilization and alteration of cervical mucus to inhibit sperm passage. The compound's stability, solubility, and metabolic pathways are essential for its effectiveness in contraceptive formulations. As with other synthetic hormones, potential side effects may include changes in mood, weight fluctuations, and alterations in menstrual patterns, necessitating careful consideration in clinical use.

Formula: C₂₂H₃₀O₂

Synonyms:

• desogestrel impurity E
• 3-beta-Hydroxyl Desogestrel
• DESOGESTREL RELATED COMPOUND B (15 MG) (3-HYDROXY-DESOGESTREL)
• (3S,8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-diol
• Desogestrel Related Compound B (3-beta-Hydroxy Desogestrel)
• 18,19-Dinorpregn-4-en-20-yne-3,17-diol, 13-ethyl-11-methylene-, (3β,17α)-
• Desogestrel EP Impurity E
• Desogestrel EP Impurity E (USP RC B)
• Desogestrel EP Impurity E (3-beta-Hydroxy Desogestrel)
• 3β-Hydroxydesogestrel
• Desogestrel EP Impurity E/Desogestrel USP RC B

Desogestrel impurity E

CAS: 70805-85-5

Desogestrel impurity E

Color and Shape: White

Ref: 47-817

Desogestrel EP Impurity E (3-β-Hydroxy Desogestrel)

CAS: 70805-85-5

Formula: C₂₂H₃₀O₂

Color and Shape: White To Off-White Solid

Molecular weight: 326.48

Ref: 4Z-D-163

13-Ethyl-11-methylidene-18,19-dinor-17α-pregn-4-en-20-yne-3β,17-diol (3β-Hydroxydesogestrel)

CAS: 70805-85-5

Color and Shape: Neat

Ref: 86-MM1024.02

3β-Hydroxydesogestrel

Controlled Product

CAS: 70805-85-5

Stability Light Sensitive
Applications 3β-Hydroxydesogestrel is a metabolite of Desogestrel (D296875), a progestogen with low androgenic potency.
References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)

Formula: C₂₂H₃₀O₂

Color and Shape: White

Molecular weight: 326.47

Ref: TR-H939005

Desogestrel EP Impurity E

CAS: 70805-85-5

Formula: C₂₂H₃₀O₂

Molecular weight: 326.5

Ref: ST-EA-CP-D35005

Desogestrel impurity E

Controlled Product

CAS: 70805-85-5

Desogestrel impurity E is a potent human endometrial carcinogen that is used in the form of conjugates with estrogens. It has been shown to be a risk factor for endometrial cancer and uterine bleeding. Catalysing the conversion of estrogen into estradiol, desogestrel impurity E is found in contraceptive steroids, most notably those that are used for on-line contraception. It also has been shown to have an effect on the liver and other organs, such as the brain and prostate gland. Desogestrel impurity E may cause cancer of the endometrium and other parts of the female reproductive system, including the ovaries and breasts.

Formula: C₂₂H₃₀O₂

Purity: Min. 95%

Molecular weight: 326.5 g/mol

Ref: 3D-FD63745