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CAS 7084-11-9

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N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE

Description:
N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride, commonly referred to as EDC, is a water-soluble carbodiimide used primarily as a coupling agent in peptide synthesis and other organic reactions. It facilitates the formation of amide bonds by activating carboxylic acids, making them more reactive towards nucleophiles, such as amines. EDC is characterized by its ability to promote the coupling of carboxylic acids and amines in aqueous solutions, which is particularly advantageous in biochemical applications. The compound is typically presented as a white to off-white crystalline powder and is hygroscopic, meaning it can absorb moisture from the air. It is important to handle EDC with care, as it can be irritating to the skin, eyes, and respiratory system. Additionally, while EDC is effective in promoting reactions, it can lead to the formation of byproducts, such as urea derivatives, which may require further purification steps. Overall, EDC is a valuable reagent in synthetic organic chemistry, particularly in the field of bioconjugation and peptide synthesis.
Formula:C8H18ClN3
InChI:InChI=1/C8H19N3.ClH/c1-4-8(9)10-6-5-7-11(2)3;/h4-7H2,1-3H3,(H2,9,10);1H
Synonyms:
  • 1-ETHYL-3-(3'-DIMETHYLAMINOPROPYL)CARBODIIMIDE, HCL
  • EDC HCL
  • EDCI HCL
  • EDC HYDROCHLORIDE
  • 1-ETHYL-3-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE MONOHYDROCHLORIDE
  • EDC
  • 1-ETHYL-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE HYDROCHLORIDE
  • 1-ETHYL-3-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE HYDROCHLORIDE
  • EDAC, HYDROCHLORIDE
  • 1-(3-DIMETHYLAMINOPROPYL)-3-ETHYLCARBODIIMIDE HYDROCHLORIDE
  • See more synonyms
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