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CAS 70874-05-4

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Cbz-D-tert-leucine

Description:
Cbz-D-tert-leucine, also known as carbobenzoxy-D-tert-leucine, is a derivative of the amino acid leucine, characterized by the presence of a carbobenzoxy (Cbz) protecting group on the amino group. This compound is typically used in peptide synthesis as a protecting group for the amino functionality, allowing for selective reactions at other functional groups. Cbz-D-tert-leucine is a white to off-white solid that is soluble in organic solvents such as dichloromethane and dimethyl sulfoxide, but has limited solubility in water. Its molecular structure includes a branched aliphatic side chain, which contributes to its hydrophobic properties. The presence of the Cbz group enhances the stability of the amino acid during synthetic procedures and can be removed under specific conditions, making it a valuable intermediate in the synthesis of peptides and other complex organic molecules. As with many chemical substances, proper handling and safety precautions should be observed, as it may pose health risks if ingested or inhaled.
Formula:C14H19NO4
InChI:InChI=1/C14H19NO4/c1-14(2,3)11(12(16)17)15-13(18)19-9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/m0/s1
SMILES:CC(C)(C)[C@H](C(=O)O)N=C(O)OCc1ccccc1
Synonyms:
  • (R)-2-(Benzyloxycarbonyl)-3,3-dimethylbutanoic acid
  • N-[(benzyloxy)carbonyl]-3-methyl-D-valine
  • Cbz-D-Alpha-T-Butylglycine
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