CAS 709-62-6

1H-1,2,4-Triazole, 3,5-bis(trifluoromethyl)-

Description:

1H-1,2,4-Triazole, 3,5-bis(trifluoromethyl)-, with CAS number 709-62-6, is a heterocyclic compound characterized by a five-membered ring containing three nitrogen atoms and two carbon atoms. This compound features two trifluoromethyl groups (-CF3) attached to the 3 and 5 positions of the triazole ring, which significantly influences its chemical properties and reactivity. The presence of these electronegative trifluoromethyl groups enhances the compound's lipophilicity and stability, making it of interest in various applications, including pharmaceuticals and agrochemicals. 1H-1,2,4-Triazole derivatives are known for their biological activity, often serving as antifungal agents or in the synthesis of other biologically active compounds. The compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. Its unique structure and functional groups contribute to its potential utility in medicinal chemistry and material science, where it can be explored for novel applications.

Formula: C₄HF₆N₃

Synonyms:

• 1H-1,2,4-TRIAZOLE,3,5-BIS(TRIFLUOROMETHYL)-

1H-1,2,4-TRIAZOLE,3,5-BIS(TRIFLUOROMETHYL)-

CAS: 709-62-6

Formula: C₄HF₆N₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 205.0613

Ref: IN-DA00FSIM

3,5-Bis(trifluoromethyl)-1H-1,2,4-triazole

CAS: 709-62-6

3,5-Bis(trifluoromethyl)-1H-1,2,4-triazole

Purity: 98%

Molecular weight: 205.06g/mol

Ref: 54-PC1005903

3,5-Bis(trifluoromethyl)-1H-1,2,4-triazole

Controlled Product

CAS: 709-62-6

Applications 3,5-Bis(trifluoromethyl)-1H-1,2,4-triazole is an intermediate in synthesizing 5-Trifluoromethyl-1H-1,2,4-triazole-3-carboxylic Acid (T791860), which is used in the synthetic preparations of neprilysin inhibitors.
References Solomon, SD., et al.: Lancet., 20, 380 (2012);

Formula: C₄HF₆N₃

Color and Shape: Off-White

Molecular weight: 205.061

Ref: TR-B585573

3,5-Bis(trifluoromethyl)-1H-1,2,4-triazole

CAS: 709-62-6

3,5-Bis(trifluoromethyl)-1H-1,2,4-triazole is a strong nucleophilic electrophile that reacts with nucleophiles to form triazolides. It can be synthesized by reacting hydroxylamine with norbornadiene in the presence of an acid catalyst such as hydrochloric acid. 3,5-Bis(trifluoromethyl)-1H-1,2,4-triazole has been shown to react with fluorine and hydrogen chloride to form a primary amino salt and a hydrochloric acid salt respectively. The reaction also generates heat energy which can be used for heating or generating electricity.

Formula: C₄HF₆N₃

Purity: Min. 95%

Molecular weight: 205.06 g/mol

Ref: 3D-AAA70962