CAS 709-63-7

4-(Trifluoromethyl)acetophenone

Description:

4-(Trifluoromethyl)acetophenone, with the CAS number 709-63-7, is an organic compound characterized by the presence of a trifluoromethyl group (-CF3) attached to the para position of an acetophenone structure. This compound typically appears as a colorless to pale yellow liquid and is known for its distinctive aromatic odor. It has a molecular formula of C9H7F3O and features a carbonyl group (C=O) that contributes to its reactivity. The trifluoromethyl group enhances the compound's lipophilicity and can influence its chemical behavior, making it useful in various synthetic applications, particularly in the field of pharmaceuticals and agrochemicals. Additionally, 4-(Trifluoromethyl)acetophenone can participate in electrophilic aromatic substitution reactions due to the electron-withdrawing nature of the trifluoromethyl group. Safety precautions should be observed when handling this compound, as it may pose health risks, including irritation to the skin and eyes. Proper storage and disposal methods are essential to mitigate environmental impact.

Formula: C₉H₇F₃O

InChI: InChI=1S/C9H7F3O/c1-6(13)7-2-4-8(5-3-7)9(10,11)12/h2-5H,1H3

InChI key: InChIKey=HHAISVSEJFEWBZ-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=CC=C(C(C)=O)C=C1

Synonyms:

• (4-Trifluoromethylphenyl) methyl ketone
• 1-Acetyl-4-(trifluoromethyl)benzene
• 1-[4-(Trifluoromethyl)Phenyl]Ethanone
• 1-[4-(Trifluoromethyl)phenyl]-1-ethanone
• 2-Bromo-2,2-Difluoroethanamine
• 4-Acetylbenzotrifluoride
• Acetophenone, 4′-(trifluoromethyl)-
• Ethanone, 1-[4-(trifluoromethyl)phenyl]-
• Methyl 4-trifluoromethylphenyl ketone
• NSC 88346
• Sodium4-trifluoromethylbenzoate
• p-(Trifluoromethyl)acetophenone
• p-Trifluoromethylacetophenone
• 4'-(Trifluoromethyl)-Acetophenone
• 4'-(Trifluoromethyl)acetophenone
• 4[-(Trifluoromethyl)acetophenone
• 4-(Trifluoromethyl) acetophenone

4'-(Trifluoromethyl)acetophenone, 98+%

CAS: 709-63-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₇F₃O

Purity: 98+%

Color and Shape: Crystals or powder or crystalline powder or fused solid, White to pale cream or pale yellow

Molecular weight: 188.15

Ref: 02-A15529

1-(4-(Trifluoromethyl)phenyl)ethanone

CAS: 709-63-7

Formula: C₉H₇F₃O

Purity: 98%

Color and Shape: Solid

Molecular weight: 188.1465

Ref: IN-DA0033U7

4'-(Trifluoromethyl)acetophenone

CAS: 709-63-7

4'-(Trifluoromethyl)acetophenone

Formula: C₉H₇F₃O

Purity: ≥95%

Color and Shape: clear. almost colourless to off white. low melting solid or liquid

Molecular weight: 188.15g/mol

Ref: 54-PC7490

4''-Trifluoromethylacetophenone

CAS: 709-63-7

Formula: C₉H₇F₃O

Molecular weight: 188.15

Ref: 7W-GK4176

4'-(Trifluoromethyl)acetophenone

CAS: 709-63-7

Formula: C₉H₇F₃O

Purity: >98.0%(GC)

Color and Shape: White or Colorless to Light yellow powder to lump to clear liquid

Molecular weight: 188.15

Ref: 3B-T1784

4′-(Trifluoromethyl)acetophenone

CAS: 709-63-7

Formula: C₉H₇F₃O

Purity: 98%

Color and Shape: Low Melting Solid

Molecular weight: 188.149

Ref: 10-F002180

4'-(Trifluoromethyl)acetophenone

CAS: 709-63-7

4'-(Trifluoromethyl)acetophenone is a phosphatase inhibitor that has been shown to have inhibitory activity against chemokines. Chemokines are a type of cytokine that are secreted by immune cells and play an important role in inflammation. 4'-(Trifluoromethyl)acetophenone has also been shown to have an effect on the cell membrane permeability of amines and 2-aminobenzyl alcohol, which are substrates for the enzyme. 4'-(Trifluoromethyl)acetophenone reacts with imidazole derivatives, such as trifluoride, forming hydrogen bonds between the two molecules. Kinetic studies have demonstrated that this reaction is reversible in solution at room temperature.

Formula: C₉H₇F₃O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 188.15 g/mol

Ref: 3D-FT28471