CAS 7091-05-6

Pregna-1,4-diene-3,20-dione, 9,11-epoxy-17,21-dihydroxy-, (9β,11β)-

Description:

Pregna-1,4-diene-3,20-dione, 9,11-epoxy-17,21-dihydroxy-, (9β,11β)-, commonly known as a synthetic steroid, exhibits several notable characteristics. This compound is a derivative of progesterone and is part of the broader class of corticosteroids, which are known for their anti-inflammatory and immunosuppressive properties. Its structure features a steroid backbone with specific functional groups, including hydroxyl and epoxy groups, which contribute to its biological activity. The presence of the 9,11-epoxy moiety is significant as it can influence the compound's interaction with steroid receptors. This substance is often studied for its potential therapeutic applications, particularly in hormone replacement therapies and in the treatment of various endocrine disorders. Additionally, its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are critical for understanding its efficacy and safety profile in clinical settings. Overall, this compound exemplifies the complexity and utility of synthetic steroids in medicinal chemistry.

Formula: C₂₁H₂₆O₅

InChI: InChI=1/C21H26O5/c1-18-7-5-13(23)9-12(18)3-4-15-14-6-8-20(25,16(24)11-22)19(14,2)10-17-21(15,18)26-17/h5,7,9,14-15,17,22,25H,3-4,6,8,10-11H2,1-2H3/t14-,15-,17-,18-,19-,20-,21+/m0/s1

InChI key: InChIKey=WQMGIEOKPKMWEY-FEUSSREZSA-N

SMILES: C[C@@]12[C@@]34[C@@](O3)(C[C@@]5(C)[C@]([C@@]4(CCC1=CC(=O)C=C2)[H])(CC[C@@]5(C(CO)=O)O)[H])[H]

Synonyms:

• (9Beta,11Beta)-17,21-Dihydroxy-9,11-Epoxypregna-1,4-Diene-3,20-Dione
• (9Beta,11Beta,17Xi)-17,21-Dihydroxy-9,11-Epoxypregna-1,4-Diene-3,20-Dione
• 9,11-Epoxy-9H-cyclopenta[a]phenanthrene, pregna-1,4-diene-3,20-dione deriv.
• 9,11β-Epoxy-17,21-dihydroxy-9β-pregna-1,4-diene-3,20-dione
• 9β-Pregna-1,4-diene-3,20-dione, 9,11β-epoxy-17,21-dihydroxy-
• Pregna-1,4-diene-3,20-dione, 9,11-epoxy-17,21-dihydroxy-, (9β,11β)-
• 9b,11b-Epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione
• Prednisolone Impurity 15
• (4aS,4bS,5aS,6aS,7R,9aS,9bS)-7-hydroxy-7-(2-hydroxyacetyl)-4a,6a-dimethyl-5a,6,6a,7,8,9,9a,9b,10,11-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2(4aH)-one
• Prednisone Impurity 1
• Prednisolone Impurity/9,11beta-Epoxy-17,21-dihydroxy-9beta-pregna-1,4-diene-3,20-dione
• Pregna-1,4-diene-3,20-dione, 9,11-epoxy-17,21-dihydroxy-, (9β,11β)- (9CI)
• 9β,11β-EPOXY-17-21-DIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE